Primary and metastatic peritoneal surface malignancies

D Cortes-Guiral, M Hübner, M Alyami, A Bhatt… - Nature Reviews …, 2021 - nature.com
Peritoneal surface malignancies comprise a heterogeneous group of primary tumours,
including peritoneal mesothelioma, and peritoneal metastases of other tumours, including …

Nanomedicine strategies for heating “cold” ovarian cancer (OC): next evolution in immunotherapy of OC

Y Yang, T Zhao, Q Chen, Y Li, Z Xiao… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has revolutionized cancer treatment, dramatically improving survival rates of
melanoma and lung cancer patients. Nevertheless, immunotherapy is almost ineffective …

Colloidal polyelectrolyte complexes from hyaluronic acid: Preparation and biomedical applications

HV Le, D Le Cerf - Small, 2022 - Wiley Online Library
Hyaluronic acid (HA) is a naturally occurring polysaccharide which has been extensively
exploited in biomedical fields owing to its outstanding biocompatibility. Self‐assembly of HA …

CO2-Driven Nebulization of pH-Sensitive Supramolecular Polymers for Intraperitoneal Hydrogel Formation and the Treatment of Peritoneal Metastasis

H Braet, PP Fransen, R Mariën, G Lollo… - … Applied Materials & …, 2023 - ACS Publications
Because peritoneal metastasis (PM) from ovarian cancer is characterized by non-specific
symptoms, it is often diagnosed at advanced stages. Pressurized intraperitoneal aerosol …

The effect of electrostatic high pressure nebulization on the stability, activity and ex vivo distribution of ionic self-assembled nanomedicines

H Braet, V Andretto, R Mariën, B Yücesan… - Acta Biomaterialia, 2023 - Elsevier
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is applied to treat unresectable
peritoneal metastasis (PM), an advanced, end-stage disease with a poor prognosis …

Hyaluronic acid: More than a carrier, having an overpowering extracellular and intracellular impact on cancer

M Bhattacharyya, H Jariyal, A Srivastava - Carbohydrate Polymers, 2023 - Elsevier
Hyaluronic acid (HA), also named hyaluronan, is an omnipresent component of the tissue
microenvironment. It is extensively used to formulate targeted drug delivery systems for …

Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions

H Braet, PP Fransen, Y Chen, S Van Herck… - Journal of Controlled …, 2023 - Elsevier
Postoperative peritoneal adhesions occur in the majority of patients undergoing intra-
abdominal surgery and are one of the leading causes of hospital re-admission. There is an …

The safe and effective intraperitoneal chemotherapy with cathepsin B-specific doxorubicin prodrug nanoparticles in ovarian cancer with peritoneal carcinomatosis

J Kim, MK Shim, YJ Cho, S Jeon, Y Moon, J Choi, J Kim… - Biomaterials, 2021 - Elsevier
Intraperitoneal (IP) chemotherapy has shown promising efficacy in ovarian cancer with
peritoneal carcinomatosis (PC), but in vivo rapid clearance and severe toxicity of free …

Carrier-free multifunctional nanomedicine for intraperitoneal disseminated ovarian cancer therapy

X Huang, M Qiu, T Wang, B Li, S Zhang… - Journal of …, 2022 - Springer
Background Ovarian cancer is the most lethal gynecological cancer which is characterized
by extensive peritoneal implantation metastasis and malignant ascites. Despite advances in …

Intraperitoneal aerosolized drug delivery: technology, recent developments, and future outlook

M Rahimi-Gorji, L Van de Sande, C Debbaut… - Advanced Drug Delivery …, 2020 - Elsevier
Current therapies for patients with peritoneal metastases (PM) are only moderately effective.
Recently, a novel locoregional treatment method for PM was introduced, consisting of a …