The unique combinations of biological, nutritional and functional properties in proteins make
them important food ingredients with the capacity to provide a range of diverse and highly …

In-vitro protein refolding is one of the key rate-limiting unit operations in manufacturing of
fusion proteins such as peptibodies expressed using E. coli. Dilution-assisted refolding is …

SARS-CoV-2 receptor-binding domain (RBD) is a major target for the development of
diagnostics, vaccines and therapeutics directed against COVID-19. Important efforts have …

Fc‐fusion proteins are highly complex molecules, difficult to manufacture at scale. In this
work, undesired proteoforms were detected during the manufacture of a therapeutic fusion …

In cancer treatment, immunotherapy has great potential for improving the prognosis of
patients with hematologic and solid malignancies. In this study, various bioinformatics tools …

PhD thesis_20210825 Page 1 Title Investigation of ER retention machinery in CHO cells for
understanding its biology and probable IgG production bottlenecks Author(s) Samy …

There continues to be an increasing demand for biotherapeutics to be commercialized for
wide range of disease areas however, there are many challenges associated with the …