The venom of the marine predatory cone snails (genus Conus) has evolved for prey capture
and defense, providing the basis for survival and rapid diversification of the now estimated …

Covering: 2012. Previous review: Nat. Prod. Rep., 2013, 30, 237–323. This review covers
the literature published in 2012 for marine natural products, with 1035 citations (673 for the …

Discovering the gene expression signature associated with a cellular state is one of the
basic quests in majority of biological studies. For most of the clinical and cellular …

Conotoxins are the peptidic components of the venoms of marine cone snails (genus
Conus). They are remarkably diverse in terms of structure and function. Unique potency and …

More than 100 species of venomous cone snails (genus Conus) are highly effective
predators of fish. The vast majority of venom components identified and functionally …

NaV1. 7 is a voltage-gated sodium ion channel implicated by human genetic evidence as a
therapeutic target for the treatment of pain. Screening fractionated venom from the tarantula …

Animal venoms represent a vast library of bioactive peptides and proteins with proven
potential, not only as research tools but also as drug leads and therapeutics. This is …

The nicotinic acetylcholine receptor (nAChR) represents the prototype of ligand-gated ion
channels. It is vital for neuromuscular transmission and an important regulator of …

Cone snails are predatory marine gastropods characterized by a sophisticated venom
apparatus responsible for the biosynthesis and delivery of complex mixtures of cysteine-rich …

Glycerids are marine annelids commonly known as bloodworms. Bloodworms have an
eversible proboscis adorned with jaws connected to venom glands. Bloodworms prey on …