Neurobiology of BDNF in fear memory, sensitivity to stress, and stress-related disorders
M Notaras, M van den Buuse - Molecular psychiatry, 2020 - nature.com
Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience
and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and …
and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and …
Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
The paraventricular thalamus controls a central amygdala fear circuit
Appropriate responses to an imminent threat brace us for adversities. The ability to sense
and predict threatening or stressful events is essential for such adaptive behaviour. In the …
and predict threatening or stressful events is essential for such adaptive behaviour. In the …
To predict, prevent, and manage post-traumatic stress disorder (PTSD): a review of pathophysiology, treatment, and biomarkers
Post-traumatic stress disorder (PTSD) can become a chronic and severely disabling
condition resulting in a reduced quality of life and increased economic burden. The disorder …
condition resulting in a reduced quality of life and increased economic burden. The disorder …
The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy
Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development,
differentiation and plasticity in both the developing and adult brain. A single-nucleotide …
differentiation and plasticity in both the developing and adult brain. A single-nucleotide …
Inflammation in post-traumatic stress disorder (PTSD): a review of potential correlates of PTSD with a neurological perspective
TD Kim, S Lee, S Yoon - Antioxidants, 2020 - mdpi.com
Post-traumatic stress disorder (PTSD) is a chronic condition characterized by symptoms of
physiological and psychosocial burden. While growing research demonstrated signs of …
physiological and psychosocial burden. While growing research demonstrated signs of …
Mechanisms of shared vulnerability to post-traumatic stress disorder and substance use disorders
CE María-Ríos, JD Morrow - Frontiers in Behavioral Neuroscience, 2020 - frontiersin.org
Psychoactive substance use is a nearly universal human behavior, but a significant minority
of people who use addictive substances will go on to develop an addictive disorder …
of people who use addictive substances will go on to develop an addictive disorder …
Mental health comorbidities in pediatric chronic pain: a narrative review of epidemiology, models, neurobiological mechanisms and treatment
Chronic pain during childhood and adolescence can lead to persistent pain problems and
mental health disorders into adulthood. Posttraumatic stress disorders and depressive and …
mental health disorders into adulthood. Posttraumatic stress disorders and depressive and …
The adolescent brain and the emergence and peak of psychopathology
A Powers, BJ Casey - Journal of Infant, Child, and Adolescent …, 2015 - Taylor & Francis
Adolescence is a period of heightened emotionality and increased risk for mental illness,
affecting as many as one in five persons. This article reviews recent human imaging and …
affecting as many as one in five persons. This article reviews recent human imaging and …
BDNF–TrkB receptor regulation of distributed adult neural plasticity, memory formation, and psychiatric disorders
Brain-derived neurotrophic factor (BDNF) and its single transmembrane receptor,
tropomysin-related kinase B (TrkB), are essential for adult synaptic plasticity and the …
tropomysin-related kinase B (TrkB), are essential for adult synaptic plasticity and the …