Nanopore technology and its applications in gene sequencing

B Lin, J Hui, H Mao - Biosensors, 2021 - mdpi.com
In recent years, nanopore technology has become increasingly important in the field of life
science and biomedical research. By embedding a nano-scale hole in a thin membrane and …

Nanopore sequencing: Review of potential applications in functional genomics

N Kono, K Arakawa - Development, growth & differentiation, 2019 - Wiley Online Library
Molecular biology has been led by various measurement technologies, and increased
throughput has developed omics analysis. The development of massively parallel …

In honor of John Bissett: authoritative guidelines on molecular identification of Trichoderma

F Cai, IS Druzhinina - Fungal Diversity, 2021 - Springer
Modern taxonomy has developed towards the establishment of global authoritative lists of
species that assume the standardized principles of species recognition, at least in a given …

Pharmacogenomics beyond single common genetic variants: the way forward

VM Lauschke, Y Zhou… - Annual Review of …, 2024 - annualreviews.org
Interindividual variability in genes encoding drug-metabolizing enzymes, transporters,
receptors, and human leukocyte antigens has a major impact on a patient's response to …

Graphene field-effect transistors as bioanalytical sensors: Design, operation and performance

A Béraud, M Sauvage, CM Bazán, M Tie, A Bencherif… - Analyst, 2021 - pubs.rsc.org
Graphene field-effect transistors (GFETs) are emerging as bioanalytical sensors, in which
their responsive electrical conductance is used to perform quantitative analyses of …

High‐throughput metagenomics for identification of pathogens in the clinical settings

N Li, Q Cai, Q Miao, Z Song, Y Fang, B Hu - Small methods, 2021 - Wiley Online Library
The application of sequencing technology is shifting from research to clinical laboratories
owing to rapid technological developments and substantially reduced costs. However …

High throughput sequencing for plant virus detection and discovery

DEV Villamor, T Ho, M Al Rwahnih, RR Martin… - …, 2019 - Am Phytopath Society
Over the last decade, virologists have discovered an unprecedented number of viruses
using high throughput sequencing (HTS), which led to the advancement of our knowledge …

The expanding landscape of alternative splicing variation in human populations

E Park, Z Pan, Z Zhang, L Lin, Y Xing - The American Journal of Human …, 2018 - cell.com
Alternative splicing is a tightly regulated biological process by which the number of gene
products for any given gene can be greatly expanded. Genomic variants in splicing …

Single-cell multiomics: multiple measurements from single cells

IC Macaulay, CP Ponting, T Voet - Trends in genetics, 2017 - cell.com
Single-cell sequencing provides information that is not confounded by genotypic or
phenotypic heterogeneity of bulk samples. Sequencing of one molecular type (RNA …

Nanopore DNA sequencing and genome assembly on the International Space Station

SL Castro-Wallace, CY Chiu, KK John, SE Stahl… - Scientific reports, 2017 - nature.com
We evaluated the performance of the MinION DNA sequencer in-flight on the International
Space Station (ISS), and benchmarked its performance off-Earth against the MinION …