Quantitative mass spectrometry-based proteomics: an overview

S Rozanova, K Barkovits, M Nikolov, C Schmidt… - Quantitative methods in …, 2021 - Springer
In recent decades, mass spectrometry has moved more than ever before into the front line of
protein-centered research. After being established at the qualitative level, the more …

A review on quantitative multiplexed proteomics

N Pappireddi, L Martin, M Wühr - Chembiochem, 2019 - Wiley Online Library
Over the last few decades, mass spectrometry‐based proteomics has become an
increasingly powerful tool that is now able to routinely detect and quantify thousands of …

Defining the carrier proteome limit for single-cell proteomics

TK Cheung, CY Lee, FP Bayer, A McCoy, B Kuster… - Nature …, 2021 - nature.com
Single-cell proteomics by mass spectrometry (SCoPE-MS) is a recently introduced method
to quantify multiplexed single-cell proteomes. While this technique has generated great …

Protein identification strategies in MALDI imaging mass spectrometry: a brief review

DJ Ryan, JM Spraggins, RM Caprioli - Current opinion in chemical biology, 2019 - Elsevier
Matrix assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a
powerful technology used to investigate the spatial distributions of thousands of molecules …

Instrumentation at the leading edge of proteomics

TM Peters-Clarke, JJ Coon, NM Riley - Analytical Chemistry, 2024 - ACS Publications
The proteome, or collection of proteoforms expressed in a biological system, is dynamic and
heterogeneous. As our appreciation for the complexity of the proteome has evolved, so have …

A tutorial review of labeling methods in mass spectrometry-based quantitative proteomics

Z Wang, PK Liu, L Li - ACS Measurement Science Au, 2024 - ACS Publications
Recent advancements in mass spectrometry (MS) have revolutionized quantitative
proteomics, with multiplex isotope labeling emerging as a key strategy for enhancing …

Enhanced multiplexing technology for proteomics

BL Bowser, RAS Robinson - Annual Review of Analytical …, 2023 - annualreviews.org
The identification of thousands of proteins and their relative levels of expression has
furthered understanding of biological processes and disease and stimulated new systems …

Chemical isotope labeling for quantitative proteomics

X Tian, HP Permentier, R Bischoff - Mass spectrometry reviews, 2023 - Wiley Online Library
Advancements in liquid chromatography and mass spectrometry over the last decades have
led to a significant development in mass spectrometry‐based proteome quantification …

Microfluidics add-on technologies for single-cell analysis

M Khan, Y Bi, G Zhang, F Yin, Y Xie, L Lin… - TrAC Trends in Analytical …, 2023 - Elsevier
Microfluidics revolutionized single-cell analysis in a way that was impossible through
conventional methods. However, microfluidic is not a stand-alone technique and cannot …

Chemo‐proteomics in antimalarial target identification and engagement

BL Bailey, W Nguyen, AF Cowman… - Medicinal Research …, 2023 - Wiley Online Library
Humans have lived in tenuous battle with malaria over millennia. Today, while much of the
world is free of the disease, areas of South America, Asia, and Africa still wage this war with …