Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels comprise a small
subfamily of proteins within the superfamily of pore-loop cation channels. In mammals, the …

The cation conductance activated upon hyperpolarization of the membrane beyond the
resting value appears to represent an ubiquitous type of membrane channel. Our …

Step hyperpolarizations evoked slowly activating, noninactivating, and slowly deactivating
inward currents from membrane patches recorded in the cell-attached patch configuration …

▪ Abstract Cyclic nucleotide–activated ion channels play a fundamental role in a variety of
physiological processes. By opening in response to intracellular cyclic nucleotides, they …

1. The hyperpolarization‐activated current (Ih) and its role in pacemaking activity in rat
hippocampal stratum oriens‐alveus interneurones was studied using whole‐cell and …

The molecular basis of the hyperpolarization‐activated cation channels that underlie the
anomalous rectifying current variously termed Ih, Iq, or If is discussed. On the basis of the …

▪ Abstract Neurons in the cochlear ganglion and auditory brain stem nuclei preserve the
relative timing of action potentials passed through sequential synaptic levels. To accomplish …

Using kinetic data from three different K+ currents in acutely isolated neurons, a single
electrical compartment representing the soma of a ventral cochlear nucleus (VCN) neuron …

Tight-seal whole-cell recordings were made from cleaned somata of CA3 pyramidal cells
deep in hippocampal slices from 19–21-d-old rats. The cells were filled with biocytin, and …

Acoustic information in auditory nerve discharges is integrated in the cochlear nuclei, and
ascends through several parallel pathways to higher centers. Octopus cells of the …