A framework for understanding the functions of biomolecular condensates across scales

AS Lyon, WB Peeples, MK Rosen - Nature Reviews Molecular Cell …, 2021 - nature.com
Biomolecular condensates are found throughout eukaryotic cells, including in the nucleus, in
the cytoplasm and on membranes. They are also implicated in a wide range of cellular …

Is plasticity of synapses the mechanism of long-term memory storage?

WC Abraham, OD Jones, DL Glanzman - NPJ science of learning, 2019 - nature.com
It has been 70 years since Donald Hebb published his formalized theory of synaptic
adaptation during learning. Hebb's seminal work foreshadowed some of the great …

Local protein synthesis is a ubiquitous feature of neuronal pre-and postsynaptic compartments

AS Hafner, PG Donlin-Asp, B Leitch, E Herzog… - Science, 2019 - science.org
INTRODUCTION The regulation of synaptic proteins by posttranslational modifications and
by ongoing protein synthesis and degradation drives homeostasis and plasticity at …

Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy

AB Harbauer, JT Hees, S Wanderoy, I Segura, W Gibbs… - Neuron, 2022 - cell.com
Summary PTEN-induced kinase 1 (PINK1) is a short-lived protein required for the removal of
damaged mitochondria through Parkin translocation and mitophagy. Because the short half …

Transmitter and receiver architectures for molecular communications: A survey on physical design with modulation, coding, and detection techniques

M Kuscu, E Dinc, BA Bilgin, H Ramezani… - Proceedings of the …, 2019 - ieeexplore.ieee.org
Inspired by nature, molecular communications (MC), ie, the use of molecules to encode,
transmit, and receive information, stands as the most promising communication paradigm to …

iLoc-lncRNA: predict the subcellular location of lncRNAs by incorporating octamer composition into general PseKNC

ZD Su, Y Huang, ZY Zhang, YW Zhao, D Wang… - …, 2018 - academic.oup.com
Abstract Motivation Long non-coding RNAs (lncRNAs) are a class of RNA molecules with
more than 200 nucleotides. They have important functions in cell development and …

[HTML][HTML] MicroRNAs shape the neuronal landscape

E McNeill, D Van Vactor - Neuron, 2012 - cell.com
The nervous system equips us with capability to adapt to many conditions and
circumstances. We rely on an armamentarium of intricately formed neural circuits for many of …

Getting around the cell: physical transport in the intracellular world

SS Mogre, AI Brown, EF Koslover - Physical Biology, 2020 - iopscience.iop.org
Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …

Neuroregeneration and plasticity: a review of the physiological mechanisms for achieving functional recovery postinjury

PG Nagappan, H Chen, DY Wang - Military Medical Research, 2020 - Springer
Neuronal networks, especially those in the central nervous system (CNS), evolved to
support extensive functional capabilities while ensuring stability. Several physiological …

Axonal transcription factors signal retrogradely in lesioned peripheral nerve

K Ben‐Yaakov, SY Dagan, Y Segal‐Ruder… - The EMBO …, 2012 - embopress.org
Retrograde axonal injury signalling stimulates cell body responses in lesioned peripheral
neurons. The involvement of importins in retrograde transport suggests that transcription …