Apparent changes in the epidemiology and severity of multiple sclerosis

N Koch-Henriksen, M Magyari - Nature Reviews Neurology, 2021 - nature.com
Multiple sclerosis (MS) is an immunological disease that causes acute inflammatory lesions
and chronic inflammation in the CNS, leading to tissue damage and disability. As awareness …

Impact of sex hormones on immune function and multiple sclerosis development

MC Ysrraelit, J Correale - Immunology, 2019 - Wiley Online Library
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) affecting young people and leading to demyelination and neurodegeneration. The …

Incidence and prevalence of multiple sclerosis in Europe: a systematic review

E Kingwell, JJ Marriott, N Jetté, T Pringsheim… - BMC neurology, 2013 - Springer
Background Multiple sclerosis (MS) is the most common cause of neurological disability in
young adults worldwide and approximately half of those affected are in Europe. The …

Sex and gender issues in multiple sclerosis

HF Harbo, R Gold, M Tintoré - Therapeutic advances in …, 2013 - journals.sagepub.com
Multiple sclerosis (MS) is universally found to be more prevalent in women than men. This
has led to extensive studies of differences in the immune system or nervous system between …

Incidence and prevalence of multiple sclerosis in the UK 1990–2010: a descriptive study in the General Practice Research Database

IS Mackenzie, SV Morant, GA Bloomfield… - Journal of Neurology …, 2014 - jnnp.bmj.com
Objectives To estimate the incidence and prevalence of multiple sclerosis (MS) by age and
describe secular trends and geographic variations within the UK over the 20-year period …

Incidence and prevalence of chronic inflammatory demyelinating polyradiculoneuropathy: a systematic review and meta-analysis

MC Broers, C Bunschoten, D Nieboer, HF Lingsma… - …, 2019 - karger.com
Background: Prevalence and incidence rates of chronic inflammatory demyelinating
polyradiculoneuropathy (CIDP) are required to determine the impact of CIDP on society. We …

Mechanisms of sex differences in Alzheimer's disease

C Lopez-Lee, ERS Torres, G Carling, L Gan - Neuron, 2024 - cell.com
Alzheimer's disease (AD) and the mechanisms underlying its etiology and progression are
complex and multifactorial. The higher AD risk in women may serve as a clue to better …

Treatment of women with multiple sclerosis planning pregnancy

KM Krysko, R Bove, R Dobson, V Jokubaitis… - … Treatment Options in …, 2021 - Springer
Abstract Purpose of Review We review data available for treatment of multiple sclerosis (MS)
before, during, and after pregnancy. We present recent data on disease-modifying therapies …

The gut microbiome and multiple sclerosis

J Ochoa-Repáraz, TO Kirby… - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
The microbiome can be defined as the sum of the microbial and host's genome. Recent
information regarding this complex organ suggests that in animal models of multiple …

The role of gender and sex hormones in determining the onset and outcome of multiple sclerosis

R Bove, T Chitnis - Multiple Sclerosis Journal, 2014 - journals.sagepub.com
Intriguing sex differences both in multiple sclerosis (MS) susceptibility and its disease course
may offer important insights into MS disease pathophysiology, prevention and treatment. In …