Chronic inflammation participates in the progression of multiple chronic diseases, including
obesity, diabetes mellitus (DM), and DM related complications. Diabetic ulcer, characterized …

The integration of several cellular responses initiates the process of wound healing. Matrix
Metalloproteinases (MMPs) play an integral role in wound healing. Their main function is …

Vitamin D deficiency has been clearly linked to major chronic diseases associated with
oxidative stress, inflammation, and aging, including cardiovascular and neurodegenerative …

Cardiovascular disease is the prevalent cause of morbidity and mortality in the world,
affecting many millions of individuals every year. Atherosclerosis, a chronic inflammatory …

Diabetic foot ulcers (DFUs) are pathological states of tissue destruction of the foot or lower
extremity in diabetic patients and are one of the serious chronic complications of diabetes …

Wound healing is a very complex process, where variety of different pathways is activated,
depending on the phase of healing. Improper or interrupted healing might result in …

Alterations of the collagen, the major structural protein in skin, contribute significantly to
human skin connective tissue aging. As aged-appearing skin is more common in diabetes …

Vitamin D deficiency has been linked to several major chronic diseases, such as
cardiovascular and neurodegenerative diseases, diabetes, and cancer, linked to oxidative …

Chronic non-healing wounds are a clinically important problem in terms of number of
patients and costs. Wound dressings such as hydrogels, hydrocolloids, polyurethane films …

Diabetic foot ulcer (DFU) is a foremost cause of amputation in diabetic patients.
Consequences of DFU include infections, decline in limb function, hospitalization …