The constructive and destructive impact of autophagy on both genders' reproducibility, a comprehensive review

M Samare-Najaf, A Neisy, A Samareh, D Moghadam… - Autophagy, 2023 - Taylor & Francis
Reproduction is characterized by a series of massive renovations at molecular, cellular, and
tissue levels. Recent studies have strongly tended to reveal the involvement of basic …

Autophagy: A challengeable paradox in cancer treatment

F Ahmadi‐Dehlaghi, P Mohammadi… - Cancer …, 2023 - Wiley Online Library
Objective Autophagy is an intracellular degradation pathway conserved in all eukaryotes
from yeast to humans. This process plays a quality‐control role by destroying harmful …

Using publicly available transcriptomic data to identify mechanistic and diagnostic biomarkers in azoospermia and overall male infertility

TS Omolaoye, MY Hachim, SS du Plessis - Scientific reports, 2022 - nature.com
Azoospermia, which is the absence of spermatozoa in an ejaculate occurring due to defects
in sperm production, or the obstruction of the reproductive tract, affects about 1% of all men …

Role of macroautophagy in mammalian male reproductive physiology

D Kirat, AM Alahwany, AH Arisha, A Abdelkhalek… - Cells, 2023 - mdpi.com
Physiologically, autophagy is an evolutionarily conserved and self-degradative process in
cells. Autophagy carries out normal physiological roles throughout mammalian life …

[HTML][HTML] Quercetin can inhibit angiogenesis via the down regulation of MALAT1 and MIAT LncRNAs in human umbilical vein endothelial cells

S Esteghlal, MJ Mokhtari, Z Beyzaei - International journal of …, 2021 - ncbi.nlm.nih.gov
Background: Angiogenesis is an important step in cancer metastasis since it enables the
growing tumor to receive nutrients and oxygen. Quercetin is a generic flavonoid and has …

The neuroprotective effects of Liuwei Dihuang medicine in the APP/PS1 mouse model are dependent on the PI3K/Akt signaling pathway

Y Yuan, Y Liu, L Hao, J Ma, S Shao, Z Yu… - Frontiers in …, 2023 - frontiersin.org
Alzheimer's disease (AD) is an age-related neurodegenerative disease that progressively
impairs cognitive function and memory. The occurrence and development of Alzheimer's …

Alteration in autophagy gene expression profile correlates with low sperm quality

Y Guo, Y Ma, J Zhang, S Jiang, G Yuan, J Cheng… - Reproductive …, 2021 - Elsevier
Aims Low sperm quality, a crucial factor of male infertility, is becoming a public health issue
all over the world. In male reproductive system, autophagy plays an important role in …

[HTML][HTML] Autophagy mediated tubulobulbar complex components degradation is required for spermiation

L Wang, R Zhang, B Wu, Y Yu, W Li, S Li, C Liu - Fundamental Research, 2022 - Elsevier
Spermiation is the process that releases mature spermatids from Sertoli cells into the lumen
of the seminiferous tubule. Tubulobulbar complexes (TBCs) are elaborate cytoskeleton …

TSGA10 as a potential key factor in the process of spermatid differentiation/maturation: deciphering its association with autophagy pathway

R Asgari, M Bakhtiari, D Rezazadeh, R Yarani… - Reproductive …, 2021 - Springer
Testis-specific gene antigen 10 (TSGA10) plays an important role in spermatogenesis.
However, the exact TSGA10 role and its relationship with the autophagy pathway in the …

[PDF][PDF] Assessment of the relationship between miR-499C/T (rs3746444) polymorphism and lung carcinoma in Iranian population; a case-control study

M Torabi, M Khafaei, B Jahanbin, M Sadeghi - African Health Sciences, 2023 - ajol.info
Assessment of the relationship between miR-499C/T (rs3746444) polymorphism and lung
carcinoma in Iranian population; a case-cont Page 1 Assessment of the relationship between …