Role of omega-3 fatty acids in cardiovascular disease: the debate continues

SCR Sherratt, P Libby, MJ Budoff, DL Bhatt… - Current atherosclerosis …, 2023 - Springer
Abstract Purpose of Review The omega-3 fatty acids (n3-FAs), eicosapentaenoic acid (EPA)
and docosahexaenoic acid (DHA), have recently undergone testing for their ability to reduce …

[HTML][HTML] Rationale and design of the Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes (PROMINENT) study

AD Pradhan, NP Paynter, BM Everett, RJ Glynn… - American Heart …, 2018 - Elsevier
Observational, genetic, and experimental data indicate that triglyceride rich lipoproteins
(TRLs) likely participate causally in atherothrombosis. Yet, robust clinical trial evidence that …

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus …

HN Ginsberg, CJ Packard, MJ Chapman… - European heart …, 2021 - academic.oup.com
Recent advances in human genetics, together with a large body of epidemiologic,
preclinical, and clinical trial results, provide strong support for a causal association between …

Dyslipidemia and cardiovascular disease risk among the MASHAD study population

M Hedayatnia, Z Asadi, R Zare-Feyzabadi… - Lipids in health and …, 2020 - Springer
Introduction Dyslipidemia may be defined as increased levels of serum total cholesterol
(TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), or a decreased serum …

Dyslipidemia in obesity: mechanisms and potential targets

B Klop, JWF Elte, M Castro Cabezas - Nutrients, 2013 - mdpi.com
Obesity has become a major worldwide health problem. In every single country in the world,
the incidence of obesity is rising continuously and therefore, the associated morbidity …

The postprandial actions of GLP-1 receptor agonists: the missing link for cardiovascular and kidney protection in type 2 diabetes

MC Thomas, MT Coughlan, ME Cooper - Cell Metabolism, 2023 - cell.com
Recent clinical trials in people with type 2 diabetes have demonstrated beneficial actions on
heart and kidney outcomes following treatment with GLP-1RAs. In part, these actions are …

Role of oxidative modifications in atherosclerosis

R Stocker, JF Keaney Jr - Physiological reviews, 2004 - journals.physiology.org
This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

Alternate day fasting and endurance exercise combine to reduce body weight and favorably alter plasma lipids in obese humans

S Bhutani, MC Klempel, CM Kroeger, JF Trepanowski… - …, 2013 - Wiley Online Library
Objective This study examined whether the combination of alternate day fasting (ADF) plus
exercise produces superior changes in body composition and plasma lipid levels when …

Triglyceride-rich lipoprotein remnants and cardiovascular disease

EK Duran, AD Pradhan - Clinical Chemistry, 2021 - academic.oup.com
Background Triglycerides, cholesterol, and their metabolism are linked due to shared
packaging and transport within circulating lipoprotein particles. While a case for a causal …

Postprandial lipemia and cardiovascular disease risk: Interrelationships between dietary, physiological and genetic determinants

KG Jackson, SD Poppitt, AM Minihane - Atherosclerosis, 2012 - Elsevier
Although the independence of the association and causality has not been fully established,
non-fasting (postprandial) triglyceride (TG) concentrations have emerged as a clinically …