Patient centric pharmaceutical drug product design—The impact on medication adherence

E Menditto, V Orlando, G De Rosa, P Minghetti… - Pharmaceutics, 2020 - mdpi.com
Medication adherence is a growing concern for public health and poor adherence to therapy
has been associated with poor health outcomes and higher costs for patients. Interventions …

Pediatric oral formulations: an updated review of commercially available pediatric oral formulations since 2007

RG Strickley - Journal of Pharmaceutical Sciences, 2019 - Elsevier
Oral pediatric formulations are either ready-to-use or require manipulation and multiuse or
single-use. Strong encouragement for preservative-free pediatric formulations has resulted …

Children's preferences for oral dosage forms and their involvement in formulation research via EPTRI (European Paediatric Translational Research Infrastructure)

E Alessandrini, F Brako, M Scarpa, M Lupo, D Bonifazi… - Pharmaceutics, 2021 - mdpi.com
The paucity of evidence-based data on formulation characteristics preferred by the children
is known to limit the design of tailored paediatric dosage forms. The European Paediatric …

Impact of tablet size and shape on the swallowability in older adults

H Hummler, C Stillhart, L Meilicke, M Grimm, E Krause… - Pharmaceutics, 2023 - mdpi.com
Older adults represent the major target population for oral medications, due to the high
prevalence of multimorbidity. To allow for successful pharmacological treatments, patients …

Challenges and innovations of drug delivery in older age

MS Khan, MS Roberts - Advanced drug delivery reviews, 2018 - Elsevier
Both drug delivery performance and various age-related physical, mental and physiological
changes can affect drug effectiveness and safety in elderly patients. The many drug delivery …

A review on taste masked multiparticulate dosage forms for paediatric

ALJ Khater, SH Almurisi, S Mahmood… - International journal of …, 2023 - Elsevier
Taste refers to those sensations perceived through taste buds on the tongue and oral cavity.
The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric …

[HTML][HTML] Innovative pharmaceutical techniques for Paediatric dosage forms: a systematic review on 3D printing, prilling/vibration and microfluidic platform

GF Racaniello, T Silvestri, M Pistone, V D'Amico… - Journal of …, 2024 - Elsevier
The production of paediatric pharmaceutical forms represents a unique challenge within the
pharmaceutical industry. The primary goal of these formulations is to ensure therapeutic …

Orodispersible Thin Film: A new patient-centered innovation

MS Gupta, TP Kumar, DV Gowda - Journal of Drug Delivery Science and …, 2020 - Elsevier
Abstract Orodispersible Thin Films (OTFs) are the most innovative and patient-centered
novel drug delivery systems. Many Pharmaceutical companies and academic experts across …

Innovations in pediatric drug formulations and administration technologies for low resource settings

SE Gerrard, J Walsh, N Bowers, S Salunke… - Pharmaceutics, 2019 - mdpi.com
Despite advances in regulations and initiatives to increase pediatric medicine development,
there is still an unmet need for age-appropriate medicines for children. The availability of …

Medication adherence and pharmaceutical design strategies for pediatric patients: An overview

Y Mu, L Zhao, L Shen - Drug Discovery Today, 2023 - Elsevier
Medication adherence in pediatric patients is a key factor in drug development and dosage
form design. High medication adherence is not only important to achieve the expected …