The essential physiological role of platelets in wound healing and tissue repair builds the
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …

Platelets are small anucleated blood cells primarily known for their vital hemostatic role.
Allogeneic platelet concentrates (PCs) collected from healthy donors are an essential …

The supplementation of culture medium with fetal bovine serum (FBS, also referred to as
“fetal calf serum”) is still common practice in cell culture applications. Due to a number of …

The use of fetal bovine serum (FBS) as a cell culture supplement is discouraged by
regulatory authorities to limit the risk of zoonoses and xenogeneic immune reactions in the …

Human platelet lysate (HPL), rich in growth factors, is an efficient alternative supplement to
fetal bovine serum (FBS) for ex vivo propagation of stromal cell-based medicinal products …

Fetal bovine serum (FBS) is used as a growth supplement in a wide range of cell culture
applications for cell-based research and therapy. However, as a xenogenic product, FBS …

Numerous cell-based therapeutics are currently being tested in clinical trials. Human platelet
lysate (HPL) is a valuable alternative to fetal bovine serum as a cell culture medium …

A pathogen-free and standardized xeno-free supplement of growth media is required for the
ex vivo propagation of human cells used as advanced therapeutic medicinal products and …

Neurodegenerative disorders of the central nervous system (CNS) and brain traumatic
insults are characterized by complex overlapping pathophysiological alterations …

Background Effective neurorestorative therapies of neurodegenerative diseases must be
developed. There is increasing interest in using human platelet lysates, rich in neurotrophic …