Allergen immunotherapy is a form of therapeutic vaccination for established IgE-mediated
hypersensitivity to common allergen sources such as pollens, house dust mites and the …

Allergen immunotherapy is effective in patients with IgE-dependent allergic rhinitis and
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …

Abstract Purpose of Review Allergic rhinitis (AR) is a chronic inflammatory immunoglobulin
(Ig) E-mediated disease of the nasal mucosa that can be triggered by the inhalation of …

Background Allergen immunotherapy (AIT) is an effective treatment for allergic
rhinoconjunctivitis (AR) with or without asthma. It is important to note that due to the complex …

Allergen-specific immunotherapy (AIT) has been used for more than 100 years as a
desensitizing therapy for IgE-mediated allergic diseases and represents a potentially …

We have prepared this document,“Sublingual Immunotherapy: World Allergy Organization
Position Paper 2013 Update”, according to the evidence-based criteria, revising and …

Sepsis is a highly lethal syndrome resulting from dysregulated immune and metabolic
responses to infection, thereby compromising host homeostasis. Activation of the …

Dendritic cells (DC) are antigen-presenting cells that can communicate with T cells both
directly and indirectly, regulating our adaptive immune responses against environmental …

Long-term efficacy that occurs with allergen immunotherapy of proven value is associated
with decreases in IgE-dependent activation of mast cells and tissue eosinophilia. This …

Human skin provides both physical integrity and immunological protection from the external
environment using functionally distinct layers, cell types and extracellular matrix. Despite its …