Neurofilament light chain protein as a marker of neuronal injury: review of its use in HIV-1 infection and reference values for HIV-negative controls

A Yilmaz, K Blennow, L Hagberg… - Expert review of …, 2017 - Taylor & Francis
Introduction: Several CSF biomarkers of neuronal injury have been studied in people living
with HIV. At this time, the most useful is the light subunit of the neurofilament protein (NFL) …

Incomplete immune recovery in HIV infection: mechanisms, relevance for clinical care, and possible solutions

JC Gaardbo, HJ Hartling, J Gerstoft… - Journal of Immunology …, 2012 - Wiley Online Library
Treatment of HIV‐infected patients with highly active antiretroviral therapy (HAART) usually
results in diminished viral replication, increasing CD4+ cell counts, a reversal of most …

Initiation of antiretroviral therapy in early asymptomatic HIV infection

Insight Start Study Group - New England Journal of Medicine, 2015 - Mass Medical Soc
Background Data from randomized trials are lacking on the benefits and risks of initiating
antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) …

First demonstration project of long-acting injectable antiretroviral therapy for persons with and without detectable human immunodeficiency virus (HIV) viremia in an …

KA Christopoulos, J Grochowski… - Clinical Infectious …, 2023 - academic.oup.com
Background Long-acting injectable antiretroviral therapy (LAI-ART) is approved for treatment-
naive or experienced people with human immunodeficiency virus (HIV; PWH) based on …

Causes of death in HIV-1—infected patients treated with antiretroviral therapy, 1996–2006: collaborative analysis of 13 HIV cohort studies

Antiretroviral Therapy Cohort … - Clinical Infectious …, 2010 - academic.oup.com
Background. We examined specific causes of mortality in human immunodeficiency virus
type 1 (HIV-1)—infected patients who initiated antiretroviral therapy (ART) in Europe and …

Factors associated with specific causes of death amongst HIV-positive individuals in the D: A: D Study

Data Collection on Adverse Events of Anti-HIV drugs (D … - Aids, 2010 - journals.lww.com
Objective: To investigate any emerging trends in causes of death amongst HIV-positive
individuals in the current cART era, and to investigate the factors associated with each …

Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society–USA panel

SM Hammer, JJ Eron, P Reiss, RT Schooley… - Jama, 2008 - jamanetwork.com
Context The availability of new antiretroviral drugs and formulations, including drugs in new
classes, and recent data on treatment choices for antiretroviral-naive and-experienced …

Major clinical outcomes in antiretroviral therapy (ART)–naive participants and in those not receiving ART at baseline in the SMART study

Strategies for Management of … - The Journal of …, 2008 - academic.oup.com
Background The SMART study randomized 5472 human immunodeficiency virus (HIV)–
infected patients with CD4+ cell counts> 350 cells/μL to intermittent antiretroviral therapy …

Serious fatal and nonfatal non-AIDS-defining illnesses in Europe

A Mocroft, P Reiss, J Gasiorowski… - JAIDS Journal of …, 2010 - journals.lww.com
Background: Little is known about the incidence and risk factors for serious non-AIDS-
defining events. Methods: The incidence of non-AIDS events (malignancies, end-stage renal …

HIV DNA is frequently present within pathologic tissues evaluated at autopsy from combined antiretroviral therapy-treated patients with undetectable viral loads

SL Lamers, R Rose, E Maidji, M Agsalda-Garcia… - Journal of …, 2016 - Am Soc Microbiol
ABSTRACT HIV infection treatment strategies have historically defined effectiveness through
measuring patient plasma HIV RNA. While combined antiretroviral therapy (cART) can …