As a major component of cell membrane lipids, Arachidonic acid (AA), being a major
component of the cell membrane lipid content, is mainly metabolized by three kinds of …

Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …

An effective resolution program may be able to prevent the progression from non-resolving
acute inflammation to persistent chronic inflammation. It has now become evident that …

Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …

Non-resolving inflammation drives the development of clinically dangerous atherosclerotic
lesions by promoting sustained plaque inflammation, large necrotic cores, thin fibrous caps …

Essential fatty acids can serve as important regulators of inflammation. A new window into
mechanisms for the resolution of inflammation was opened with the identification and …

Asthma is a prevalent disease of chronic inflammation in which endogenous
counterregulatory signaling pathways are dysregulated. Recent evidence suggests that …

Allergic inflammation is due to a complex interplay between several inflammatory cells,
including mast cells, basophils, lymphocytes, dendritic cells, eosinophils, and sometimes …

Omega-3 fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are
found naturally in fish oil and are commonly thought to be anti-inflammatory nutrients, with …

Acute inflammation in the lung is essential to health. So too is its resolution. In response to
invading microbes, noxious stimuli, or tissue injury, an acute inflammatory response is …