Innate immune responses in leprosy
Leprosy is an infectious disease that may present different clinical forms depending on host
immune response to Mycobacterium leprae. Several studies have clarified the role of …
immune response to Mycobacterium leprae. Several studies have clarified the role of …
Host immune-metabolic adaptations upon mycobacterial infections and associated co-morbidities
Mycobacterial diseases are a major public health challenge. Their causative agents include,
in order of impact, members of the Mycobacterium tuberculosis complex (causing …
in order of impact, members of the Mycobacterium tuberculosis complex (causing …
[HTML][HTML] New insights into the pathogenesis of leprosy: contribution of subversion of host cell metabolism to bacterial persistence, disease progression, and …
Chronic infection by the obligate intracellular pathogen Mycobacterium leprae may lead to
the development of leprosy. Of note, in the lepromatous clinical form of the disease, failure of …
the development of leprosy. Of note, in the lepromatous clinical form of the disease, failure of …
Elevated heme impairs macrophage phagocytosis in endometriosis
YY Liu, YK Liu, WT Hu, LL Tang, YR Sheng… - …, 2019 - rep.bioscientifica.com
Endometriosis (EMS) is a chronic inflammatory disease characterized by the presence of
extrauterine endometrial tissues. It has been previously reported that the refluxed blood …
extrauterine endometrial tissues. It has been previously reported that the refluxed blood …
Type I interferons, autophagy and host metabolism in leprosy
TG Toledo Pinto, LR Batista-Silva… - Frontiers in …, 2018 - frontiersin.org
For those with leprosy, the extent of host infection by Mycobacterium leprae and the
progression of the disease depend on the ability of mycobacteria to shape a safe …
progression of the disease depend on the ability of mycobacteria to shape a safe …
Reanalysis and integration of public microarray datasets reveals novel host genes modulated in leprosy
T Leal-Calvo, MO Moraes - Molecular Genetics and Genomics, 2020 - Springer
Due to multiple hypothesis testing with often limited sample size, microarrays and other—
omics technologies can sometimes produce irreproducible findings. Complementary to …
omics technologies can sometimes produce irreproducible findings. Complementary to …
Autophagy impairment is associated with increased inflammasome activation and reversal reaction development in multibacillary leprosy
MG de Mattos Barbosa, BJ de Andrade Silva… - Frontiers in …, 2018 - frontiersin.org
Leprosy reactions are responsible for incapacities in leprosy and represent the major cause
of permanent neuropathy. The identification of biomarkers able to identify patients more …
of permanent neuropathy. The identification of biomarkers able to identify patients more …
[HTML][HTML] Advances in the pathogenic, genetic and immunological studies of leprosy
Z Mi, H Liu, F Zhang - hLife, 2024 - Elsevier
Leprosy is an infectious granulomatous disease caused by Mycobacterium leprae that
affects the skin and can lead to deformity by damaging peripheral nerves. Although leprosy …
affects the skin and can lead to deformity by damaging peripheral nerves. Although leprosy …
Neutrophil NETworking in ENL: potential as a putative biomarker: future insights
Erythema nodosum leprosum (ENL), also known as type 2 reaction (T2R) is an immune
complex mediated (type III hypersensitivity) reactional state encountered in patients with …
complex mediated (type III hypersensitivity) reactional state encountered in patients with …
M2 macrophages participate in ILC2 activation induced by Helicobacter pylori infection
R Peng, C Xu, L Zhang, X Liu, D Peng, X Chen… - Gut …, 2024 - Taylor & Francis
Helicobacter pylori (H. pylori) causes a diversity of gastric diseases. The host immune
response evoked by H. pylori infection is complicated and can influence the development …
response evoked by H. pylori infection is complicated and can influence the development …