Interpreting the Kansas City Cardiomyopathy Questionnaire in Clinical Trials and Clinical Care: JACC State-of-the-Art Review

JA Spertus, PG Jones, AT Sandhu, SV Arnold - Journal of the American …, 2020 - jacc.org
To improve the patient-centeredness of care, patient-reported outcomes have been
increasingly used to quantify patients' symptoms, function, and quality of life. In heart failure …

Basic mechanisms of diabetic heart disease

RH Ritchie, ED Abel - Circulation Research, 2020 - Am Heart Assoc
Diabetes mellitus predisposes affected individuals to a significant spectrum of
cardiovascular complications, one of the most debilitating in terms of prognosis is heart …

[HTML][HTML] The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

ME Nassif, SL Windsor, BA Borlaug, DW Kitzman… - Nature medicine, 2021 - nature.com
Patients with heart failure and preserved ejection fraction (HFpEF) have a high burden of
symptoms and functional limitations, and have a poor quality of life. By targeting …

American Association of Clinical Endocrinology clinical practice guideline: developing a diabetes mellitus comprehensive care plan—2022 update

L Blonde, GE Umpierrez, SS Reddy, JB McGill… - Endocrine Practice, 2022 - Elsevier
Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

[HTML][HTML] The SGLT2 inhibitor canagliflozin in heart failure: the CHIEF-HF remote, patient-centered randomized trial

JA Spertus, MC Birmingham, M Nassif, CV Damaraju… - Nature medicine, 2022 - nature.com
Large traditional clinical trials suggest that sodium-glucose co-transporter 2 inhibitors
improve symptoms in patients with heart failure and reduced ejection fraction (HFrEF) and in …

Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial

JA Lindenfeld, MR Zile, AS Desai, K Bhatt, A Ducharme… - The Lancet, 2021 - thelancet.com
Background Previous studies have suggested that haemodynamic-guided management
using an implantable pulmonary artery pressure monitor reduces heart failure …

2021 update to the 2017 ACC expert consensus decision pathway for optimization of heart failure treatment: answers to 10 pivotal issues about heart failure with …

TM Maddox, JL Januzzi Jr, LA Allen, K Breathett… - Journal of the American …, 2021 - jacc.org
Abstract The 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart
Failure Treatment was created to provide a practical, streamlined resource for clinicians …

Randomized trial of empagliflozin in nondiabetic patients with heart failure and reduced ejection fraction

CG Santos-Gallego, AP Vargas-Delgado… - Journal of the American …, 2021 - jacc.org
Background Large clinical trials established the benefits of sodium-glucose cotransporter 2
inhibitors in patients with diabetes and with heart failure with reduced ejection fraction …

Effect of empagliflozin on the clinical stability of patients with heart failure and a reduced ejection fraction: the EMPEROR-Reduced trial

M Packer, SD Anker, J Butler, G Filippatos, JP Ferreira… - Circulation, 2021 - Am Heart Assoc
Background: Empagliflozin reduces the risk of cardiovascular death or hospitalization for
heart failure in patients with heart failure and a reduced ejection fraction, with or without …

2020 expert consensus decision pathway on novel therapies for cardiovascular risk reduction in patients with type 2 diabetes: a report of the American College of …

SR Das, BM Everett, KK Birtcher, JM Brown… - Journal of the American …, 2020 - jacc.org
2020 Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk
Reduction in Patients With Type 2 Diabetes: A Report of the American College of …