Pathophysiology and mechanism of long COVID: a comprehensive review

D Castanares-Zapatero, P Chalon, L Kohn… - Annals of …, 2022 - Taylor & Francis
Background After almost 2 years of fighting against SARS-CoV-2 pandemic, the number of
patients enduring persistent symptoms long after acute infection is a matter of concern. This …

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

2022 ACC expert consensus decision pathway on cardiovascular sequelae of COVID-19 in adults: myocarditis and other myocardial involvement, post-acute …

Writing Committee, TJ Gluckman, NM Bhave… - Journal of the American …, 2022 - jacc.org
The American College of Cardiology (ACC) has a long history of developing documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …

[HTML][HTML] Post-acute COVID-19 syndrome

A Nalbandian, K Sehgal, A Gupta, MV Madhavan… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen
responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in …

A molecular single-cell lung atlas of lethal COVID-19

JC Melms, J Biermann, H Huang, Y Wang, A Nair… - Nature, 2021 - nature.com
Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2
infection,, but the host response at the lung tissue level is poorly understood. Here we …

[HTML][HTML] Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19

PA Szabo, P Dogra, JI Gray, SB Wells, TJ Connors… - Immunity, 2021 - cell.com
Immune response dynamics in coronavirus disease 2019 (COVID-19) and their severe
manifestations have largely been studied in circulation. Here, we examined the relationship …

[HTML][HTML] Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology

R Bussani, E Schneider, L Zentilin, C Collesi, H Ali… - …, 2020 - thelancet.com
Background COVID-19 is a deadly pulmonary disease with peculiar characteristics, which
include variable clinical course and thrombophilia. A thorough understanding of the …

Pathophysiology of SARS-CoV-2: the Mount Sinai COVID-19 autopsy experience

C Bryce, Z Grimes, E Pujadas, S Ahuja, MB Beasley… - Modern …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated clinical
syndrome COVID-19 are causing overwhelming morbidity and mortality around the globe …

Myocarditis is rare in COVID-19 autopsies: cardiovascular findings across 277 postmortem examinations

MK Halushka, RS Vander Heide - Cardiovascular Pathology, 2021 - Elsevier
The COVID-19 pandemic, the result of severe acute respiratory syndrome (SARS)-CoV-2, is
a major cause of worldwide mortality with a significant cardiovascular component. While a …

Long-term lung abnormalities associated with COVID-19 pneumonia

JP Kanne, BP Little, JJ Schulte, A Haramati… - Radiology, 2022 - pubs.rsna.org
In the 3rd year of the SARS-CoV-2 pandemic, much has been learned about the long-term
effects of COVID-19 pneumonia on the lungs. Approximately one-third of patients with …