In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Tissue engineering (TE) has brought new hope for articular cartilage regeneration, as TE
can provide structural and functional substitutes for native tissues. The basic elements of TE …

Cartilage grafts generated using conventional static tissue engineering strategies are
characterised by low cell viability, suboptimal hyaline cartilage formation and, critically …

Articular cartilage (AC) is the weight-bearing tissue in diarthroses. It lacks the capacity for
self-healing once there are injuries or diseases due to its avascularity. With the development …

Ultrasonic fields are able to exert forces on cells and other micron-scale particles, including
microbubbles. The technology is compatible with existing lab-on-chip techniques and is …

Parkinson's disease (PD) is characterized by the decrease of dopamine (DA) production and
release in the substantia nigra and striatum regions of the brain. Transcranial ultrasound has …

This study provides evidence that low-intensity ultrasound directly affects nuclear processes,
and the magnitude of the effect varies with frequency. In particular, we show that the …

Recapitulation of multiscale structure–function properties of cells, cell‐secreted extracellular
matrix, and 3D architecture of natural tissues is central to engineering biomimetic tissue …

Background Cartilage repair outcomes are compromised in a pro-inflammatory environment;
therefore, the mitigation of pro-inflammatory responses is beneficial. Treatment with …

The primary cilium has been implicated in mechanotransduction, however, its
mechanosensory role in transducing signals under low-intensity ultrasound (LIUS) which …