TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate
MP Hernández-Mitre… - Clinical …, 2024 - clinicalmicrobiologyandinfection …
Background Synthetic serine protease inhibitors block the cellular enzyme transmembrane
protease serine 2, thus preventing SARS-CoV-2 cell entry. There are two relevant drugs in …
protease serine 2, thus preventing SARS-CoV-2 cell entry. There are two relevant drugs in …
TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of nafamostat and camostat mesylate randomised clinical trials
HMM Patricia, M Susan, V Balasubramanian… - Clinical Microbiology …, 2024 - Elsevier
Background Synthetic serine protease inhibitors block the cellular enzyme transmembrane
protease serine 2 (TMPRSS2) preventing SARS-CoV-2 cell entry. There are two relevant …
protease serine 2 (TMPRSS2) preventing SARS-CoV-2 cell entry. There are two relevant …
Host Receptor Targeting to Treat Covid-19
JD Gunst, OS Søgaard - NEJM evidence, 2023 - evidence.nejm.org
Not long after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was
identified as the cause of coronavirus disease 2019 (Covid-19), in vitro experiments …
identified as the cause of coronavirus disease 2019 (Covid-19), in vitro experiments …
Prior Ground: Selection of Prior Distributions When Analyzing Clinical Trial Data Using Bayesian Methods
J Siddique, Z Aghabazaz - NEJM evidence, 2023 - evidence.nejm.org
Increasingly, investigators are choosing to use Bayesian methods for the analysis of clinical
trial data. Unlike classical statistical methods that treat model parameter values (such as …
trial data. Unlike classical statistical methods that treat model parameter values (such as …
Clinician perceptions of research priorities for the management of noncritically ill patients admitted to hospital with SARS‐CoV‐2 infection
MM Bandara, LA Barina, GM McPhee… - Internal Medicine …, 2024 - Wiley Online Library
The changing phenotype of coronarvirus disease 2019 (COVID‐19) may quickly render
guideline‐recommended interventions obsolete. We developed a 40‐question clinician …
guideline‐recommended interventions obsolete. We developed a 40‐question clinician …