Folate receptor-mediated delivery of mitoxantrone-loaded solid lipid nanoparticles to breast cancer cells

A Granja, C Nunes, CT Sousa, S Reis - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The standard breast cancer therapy still faces major challenges due to non-specific tumor
distribution and occurrence of dose-limiting adverse side-effects. Nanomedicine constitutes …

Aquatic toxicity of manufactured nanomaterials: challenges and recommendations for future toxicity testing

AG Schultz, D Boyle, D Chamot, KJ Ong… - Environmental …, 2014 - CSIRO Publishing
Environmental context The increased use of nanomaterials in industrial and consumer
products requires robust strategies to identify risks when they are released into the …

Designer nanoparticles for plant cell culture systems: Mechanisms of elicitation and harnessing of specialized metabolites

SS Arya, SK Lenka, DM Cahill, JE Rookes - BioEssays, 2021 - Wiley Online Library
Plant cell culture systems have become an attractive and sustainable approach to produce
high‐value and commercially significant metabolites under controlled conditions. Strategies …

Meta-analysis of nanoparticle cytotoxicity via data-mining the literature

HI Labouta, N Asgarian, K Rinker, DT Cramb - ACS nano, 2019 - ACS Publications
Developing predictive modeling frameworks of potential cytotoxicity of engineered
nanoparticles is critical for environmental and health risk analysis. The complexity and the …

Silver nanoparticles reduce brain inflammation and related neurotoxicity through induction of H2S-synthesizing enzymes

DA Gonzalez-Carter, BF Leo, P Ruenraroengsak… - Scientific reports, 2017 - nature.com
Silver nanoparticles (AgNP) are known to penetrate into the brain and cause neuronal
death. However, there is a paucity in studies examining the effect of AgNP on the resident …

[HTML][HTML] Cyto and genotoxicity of gold nanoparticles in human hepatocellular carcinoma and peripheral blood mononuclear cells

IMM Paino, VS Marangoni, RCS de Oliveira… - Toxicology letters, 2012 - Elsevier
Engineered nanomaterials have been extensively applied as active materials for
technological applications. Since the impact of these nanomaterials on health and …

Transcriptome sequencing (RNA-seq) analysis of the effects of metal nanoparticle exposure on the transcriptome of Chlamydomonas reinhardtii

DF Simon, RF Domingos, C Hauser… - Applied and …, 2013 - Am Soc Microbiol
The widespread use of nanoparticles (NPs) raises concern over their potential toxicological
effects in humans and ecosystems. Here we used transcriptome sequencing (RNA-seq) to …

Nanoparticle administration method in cell culture alters particle-cell interaction

TL Moore, DA Urban, L Rodriguez-Lorenzo… - Scientific reports, 2019 - nature.com
As a highly interdisciplinary field, working with nanoparticles in a biomedical context
requires a robust understanding of soft matter physics, colloidal behaviors, nano …

Oxidative stress contributes to gold nanoparticle-induced cytotoxicity in human tumor cells

D Mateo, P Morales, A Ávalos… - … mechanisms and methods, 2014 - Taylor & Francis
Due to their exceptional properties, gold nanoparticles (AuNPs) have shown promising
medical and technological applications in the treatment of cancer and the development of …

Fluorescent plastic nanoparticles to track their interaction and fate in physiological environments

J Caldwell, R Lehner, S Balog, C Rhême… - Environmental …, 2021 - pubs.rsc.org
As the prevalence of plastic micro-and nanoparticles in the environment, foods, and
beverages continues to increase, the risk of human exposure to and uptake of such …