Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …

Clinical observations suggest a complex relationship between human obesity and
cardiovascular disease. Whilst abdominal (visceral) adiposity leads to deleterious metabolic …

White adipose tissue displays high plasticity. We developed a system for the inducible,
permanent labeling of mature adipocytes that we called the AdipoChaser mouse. We …

The sexually dimorphic distribution of adipose tissue influences the development of obesity-
associated pathologies. The accumulation of visceral white adipose tissue (VWAT) that …

Polycystic ovary syndrome (PCOS), a complex condition that affects women of reproductive
age, is characterized by ovulatory dysfunction and androgen excess. Women with PCOS …

Over the last decade, stem cell-based regenerative medicine has progressed to clinical
testing and therapeutic applications. The applications range from infusions of autologous …

Adipose tissue is formed at stereotypic times and locations in a diverse array of organisms.
Once formed, the tissue is dynamic, responding to homeostatic and external cues and …

White adipose tissue (WAT) is a cellularly heterogeneous endocrine organ that not only
serves as an energy reservoir, but also actively participates in metabolic homeostasis …

The obesity epidemic has intensified efforts to understand the mechanisms controlling
adipose tissue development. Adipose tissue is generally classified as white adipose tissue …

Obesity is a strong risk factor for cancer progression, posing obesity-related cancer as one of
the leading causes of death. Nevertheless, the molecular mechanisms that endow cancer …