Intranasal oxytocin in the treatment of autism spectrum disorders: A multilevel meta-analysis

Y Huang, X Huang, RP Ebstein, R Yu - Neuroscience & Biobehavioral …, 2021 - Elsevier
Intranasal oxytocin has been shown to promote social functioning and has recently been
applied as a treatment for autism spectrum disorders (ASD). The current meta-analysis aims …

The role of central serotonin neurons and 5-HT heteroreceptor complexes in the pathophysiology of depression: a historical perspective and future prospects

DO Borroto-Escuela, P Ambrogini… - International journal of …, 2021 - mdpi.com
Serotonin communication operates mainly in the extracellular space and cerebrospinal fluid
(CSF), using volume transmission with serotonin moving from source to target cells (neurons …

A comparison of methods to measure central and peripheral oxytocin concentrations in human and non-human primates

A Lefevre, R Mottolese, M Dirheimer, C Mottolese… - Scientific Reports, 2017 - nature.com
Oxytocin (OT) concentration in the blood is considered to be a marker of its action in the
brain. However, two problems have emerged when measuring OT level in the blood. First, it …

Overcoming Depression with 5-HT2A Receptor Ligands

A Zięba, P Stępnicki, D Matosiuk… - International Journal of …, 2021 - mdpi.com
Depression is a multifactorial disorder that affects millions of people worldwide, and none of
the currently available therapeutics can completely cure it. Thus, there is a need for …

Serotonin transporter availability in adults with autism—a positron emission tomography study

M Andersson, Ä Tangen, L Farde, S Bölte… - Molecular …, 2021 - nature.com
Impairments in social interaction and communication, in combination with restricted,
repetitive behaviors and interests, define the neurodevelopmental diagnosis of autism …

Daily intake of Lactobacillus alleviates autistic-like behaviors by ameliorating the 5-hydroxytryptamine metabolic disorder in VPA-treated rats during weaning and …

Q Kong, B Wang, P Tian, X Li, J Zhao, H Zhang… - Food & Function, 2021 - pubs.rsc.org
Probiotic therapy targeting gut-brain axis has been proven to be effective in treating autistic
patients. The present study aimed to assess the ability of three Lactobacillus strains (L …

Interplay between the oxytocin and opioid systems in regulating social behaviour

PT Putnam, SWC Chang - Philosophical Transactions of …, 2022 - royalsocietypublishing.org
The influence of neuromodulators on brain activity and behaviour is undeniably profound,
yet our knowledge of the underlying mechanisms, or ability to reliably reproduce effects …

The role of oxytocin in abnormal brain development: effect on glial cells and neuroinflammation

M Knoop, ML Possovre, A Jacquens, A Charlet, O Baud… - Cells, 2022 - mdpi.com
The neonatal period is critical for brain development and determinant for long-term brain
trajectory. Yet, this time concurs with a sensitivity and risk for numerous brain injuries …

[HTML][HTML] Fear, love, and the origins of canid domestication: An oxytocin hypothesis

YE Herbeck, M Eliava, V Grinevich… - Comprehensive …, 2022 - Elsevier
The process of dog domestication likely involved at least two functional stages. The initial
stage occurred when subpopulations of wolves became synanthropes, benefiting from life …

Sexual health and serotonin 4 receptor brain binding in unmedicated patients with depression—a NeuroPharm study

AL Rasmussen, SV Larsen, B Ozenne… - Translational …, 2023 - nature.com
Sexual dysfunction is prominent in Major Depressive Disorder (MDD) and affects women
with depression more than men. Patients with MDD relative to healthy controls have lower …