Co-infection with Mycobacterium tuberculosis is the leading cause of death in individuals
infected with HIV-1. It has long been known that HIV-1 infection alters the course of M …

Epidemiological studies are providing strong evidence on beneficial health effects from
dietary measures, leading scientists to actively investigate which foods and which specific …

While a third of the world carries the burden of tuberculosis, disease control has been
hindered by a lack of tools, including a rapid, point-of-care diagnostic and a protective …

Tuberculosis (TB) and human immunodeficiency virus/acquired immunodeficiency
syndrome (HIV/AIDS) constitute the main burden of infectious disease in resource-limited …

Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …

To generate vaccine-mediated protection is a complex challenge. Currently available
vaccines have largely been developed empirically, with little or no understanding on how …

Breakthrough findings in the clinical and preclinical development of tuberculosis (TB)
vaccines have galvanized the field and suggest, for the first time since the development of …

Tuberculosis (TB) vaccine research has reached a unique point in time. Breakthrough
findings in both the basic immunology of Mycobacterium tuberculosis infection and the …

Molecular mechanisms for T-cell immune responses modulated by T cell-inhibitory
molecules during tuberculosis (TB) infection remain unclear. Here, we show that active …

Lack of access to human tissues with untreated tuberculosis (TB) has forced generations of
researchers to use animal models and to adopt a paradigm that granulomas are the …