This review summarizes our current knowledge of human disease-relevant genetic variants
within the family of voltage gated Ca2+ channels. Ca2+ channelopathies cover a wide …

Objective To review characteristics and outcomes of all cases of visual snow seen at our
institution, with attention to possible triggering events or comorbidities. Methods This is a …

Despite numerous studies concerning the pathophysiology of migraine, the exact molecular
mechanism of disturbances underlying migraine is still unknown. Furthermore, oxidative …

Migraine and major depression are debilitating disorders with high lifetime prevalence rates.
Interestingly these disorders are highly comorbid and show significant heritability …

Migraine is the second most prevalent disorder in the world; yet, its underlying mechanisms
are still poorly understood. Cumulative studies have revealed pivotal roles of cerebral cortex …

Migraine is a complex brain disorder, characterized by attacks of unilateral headache and
global dysfunction in multisensory information processing, whose underlying cellular and …

Background Migraine affects a significant fraction of the world population, yet its etiology is
not completely understood. In vitro results highlighted thalamocortical and intra-cortical …

Background Chronic migraine is closely related to the dysregulation of neurochemical
substances in the brain, with metabolic imbalance being one of the proposed causes of …

A key unanswered question in migraine neurobiology concerns the mechanisms that make
the brain of migraineurs susceptible to cortical spreading depression (CSD, a spreading …

Glutamate levels and lifetime in the brain extracellular space are dinamically regulated by a
family of Na+-and K+-dependent glutamate transporters, which thereby control numerous …