Novel trends in hydrogel development for biomedical applications: A review

P Sánchez-Cid, M Jiménez-Rosado, A Romero… - Polymers, 2022 - mdpi.com
Nowadays, there are still numerous challenges for well-known biomedical applications,
such as tissue engineering (TE), wound healing and controlled drug delivery, which must be …

Multifunctional hydrogels for the healing of diabetic wounds

T Xiang, Q Guo, L Jia, T Yin, W Huang… - Advanced …, 2024 - Wiley Online Library
The healing of diabetic wounds is hindered by various factors, including bacterial infection,
macrophage dysfunction, excess proinflammatory cytokines, high levels of reactive oxygen …

Construction of multifunctional wound dressings with their application in chronic wound treatment

L Long, W Liu, C Hu, L Yang, Y Wang - Biomaterials science, 2022 - pubs.rsc.org
As the prevalence of diabetes increases year by year and the aging population continues to
intensify in the world, chronic wounds such as diabetic foot ulcers and pressure ulcers have …

Regeneration of infarcted hearts by myocardial infarction-responsive injectable hydrogels with combined anti-apoptosis, anti-inflammatory and pro-angiogenesis …

C Hu, W Liu, L Long, Z Wang, W Zhang, S He, L Lu… - Biomaterials, 2022 - Elsevier
Current treatments including drug therapy, medical device implantation, and organ
transplantation have considerable shortcomings for myocardial infarction (MI), such as high …

3D‐Printed Functional Hydrogel by DNA‐Induced Biomineralization for Accelerated Diabetic Wound Healing

N Kim, H Lee, G Han, M Kang, S Park… - Advanced …, 2023 - Wiley Online Library
Chronic wounds in diabetic patients are challenging because their prolonged inflammation
makes healing difficult, thus burdening patients, society, and health care systems …

A simple yet effective hydrogel dressing for advanced microenvironmental management of diabetic wounds with intrinsic regulation

K Liu, Y Kang, X Dong, Q Li, Y Wang, X Wu… - Chemical Engineering …, 2023 - Elsevier
Diabetic wounds are challenging to heal due to high glucose levels, and oxidative stress,
impaired immune response and delayed angiogenesis. Hydrogel dressings capable of …

Clickable and smart drug delivery vehicles accelerate the healing of infected diabetic wounds

M Deng, Y Wu, Y Ren, H Song, L Zheng, G Lin… - Journal of Controlled …, 2022 - Elsevier
In this study, an adipic acid dihydrazide (ADH)/tannic acid (TA)-grafted hyaluronic acid (HA)-
based multifunctional hydrogel was synthesized through a spontaneous amino-yne click …

Functional carbohydrate-based hydrogels for diabetic wound therapy

Y Zhang, Y Zhu, P Ma, H Wu, D Xiao, Y Zhang… - Carbohydrate …, 2023 - Elsevier
Diabetes wound are grave and universal complications of diabetes. Owing to poor treatment
course, high amputation rate and mortality, diabetes wound treatment and care have …

In situ hydrogel capturing nitric oxide microbubbles accelerates the healing of diabetic foot

Y Zhao, L Luo, L Huang, Y Zhang, M Tong… - Journal of Controlled …, 2022 - Elsevier
Diabetic foot ulcer (DFU) is a devastating complication in diabetes patients, imposing a high
risk of amputation and economic burden on patients. Sustained inflammation and …

Intelligent biobased hydrogels for diabetic wound healing: A review

H Wang, LM Zhang - Chemical Engineering Journal, 2024 - Elsevier
Slow wound healing induces great pain in diabetic patients. However, developing new
approaches to promote diabetic wound healing is still one of the toughest challenges. This …