Heart failure in pediatric patients with congenital heart disease

RB Hinton, SM Ware - Circulation research, 2017 - Am Heart Assoc
Heart failure (HF) is a complex clinical syndrome resulting from diverse primary and
secondary causes and shared pathways of disease progression, correlating with substantial …

[HTML][HTML] New trends in heart regeneration: a review

A Kochegarov, LF Lemanski - Journal of stem cells & Regenerative …, 2016 - ncbi.nlm.nih.gov
In this review, we focus on new approaches that could lead to the regeneration of heart
muscle and the restoration of cardiac muscle function derived from newly-formed …

Cardiac stem cell therapy: Does a newborn infant's heart have infinite potential for stem cell therapy?

S Sano, T Sano, S Ishigami, T Ito - The Journal of Thoracic and …, 2022 - jtcvs.org
Feature Editor's Introduction––The recent decade has witnessed unprecedented research
activity in the field of myocardial regeneration with particular enthusiasm displayed around …

[HTML][HTML] Regenerative therapies in young hearts with structural or congenital heart disease

I Michel-Behnke, I Pavo, S Recla, M Khalil… - Translational …, 2019 - ncbi.nlm.nih.gov
Pediatric heart failure (HF) is rare. The prognosis is generally poor. HF is most frequently
related to cardiomyopathy or congenital heart disease (CHD). Associated phenotypes are …

RETRACTED ARTICLE: Transient Activation of Reprogramming Transcription Factors Using Protein Transduction Facilitates Conversion of Human Fibroblasts …

Z Ghazizadeh, H Rassouli, H Fonoudi, M Alikhani… - Molecular …, 2017 - Springer
Derivation of cardiomyocytes directly from patients' own fibroblasts could offer a new
therapeutic approach for those with ischemic heart disease. An essential step toward clinical …

Lipopolysaccharide pretreatment promotes cardiac stem cell migration through heat shock protein 90-dependent β-catenin activation

L Zhang, WR Geng, J Hu, XM Chen, YL Shen, LL Wang… - Life sciences, 2016 - Elsevier
Aims To investigate the effect of lipopolysaccharide (LPS) on the migration of cardiac stem
cells (CSCs) and whether β-catenin is involved in its underlying mechanism. Main methods …

Rejuvenation and Regenerative Potential of Heart Stem Cells

MI Nasser, H Zhongyu, D Gang, M Muqadas… - … Applications of Stem …, 2023 - Springer
Cardiovascular diseases, more precisely myocardial infarction, are the leading cause of
mortality on a global scale resulting in a widespread loss of functional cardiomyocytes. Thus …

[HTML][HTML] Clinical cardiac regenerative studies in children

IJ Pavo, I Michel-Behnke - World Journal of Cardiology, 2017 - ncbi.nlm.nih.gov
Although the incidence of pediatric heart failure is low, the mortality is relatively high, with
severe clinical symptoms requiring repeated hospitalization or intensive care treatment in …

From safety to benefit in cell delivery during surgical repair of Ebstein anomaly: initial results

KA Holst, JA Dearani, MY Qureshi, P Wackel… - The Annals of Thoracic …, 2022 - Elsevier
Background The objective of this study is to assess the safety and early impact of
intramyocardial delivery of autologous bone marrow–derived mononuclear cells (BM-MNC) …

RETRACTED ARTICLE: Transient Activation of Reprogramming Transcription Factors Using Protein Transduction Facilitates Conversion of Human Fibroblasts …

G Zaniar, R Hassan, F Hananeh, A Mehdi… - Molecular …, 2017 - search.proquest.com
Derivation of cardiomyocytes directly from patients' own fibroblasts could offer a new
therapeutic approach for those with ischemic heart disease. An essential step toward clinical …