A systematic review of the biological mediators of fat taste and smell

RB Jaime-Lara, BE Brooks, C Vizioli… - Physiological …, 2023 - journals.physiology.org
Taste and smell play a key role in our ability to perceive foods. Overconsumption of highly
palatable energy-dense foods can lead to increased caloric intake and obesity. Thus there is …

Olfaction in the context of obesity and diabetes: insights from animal models to humans

M Faour, C Magnan, H Gurden, C Martin - Neuropharmacology, 2022 - Elsevier
The olfactory system is at the crossroad between sensory processing and metabolic
sensing. In addition to being the center of detection and identification of food odors, it is a …

Reduced olfactory bulb volume in obesity and its relation to metabolic health status

M Poessel, N Breuer, A Joshi, A Pampel… - Frontiers in human …, 2020 - frontiersin.org
Smell perception plays an important role in eating behavior and might be involved in body
weight gain. Since a body of literature implies that olfactory perception and function is …

Type 2 diabetes impairs odour detection, olfactory memory and olfactory neuroplasticity; effects partly reversed by the DPP-4 inhibitor Linagliptin

G Lietzau, W Davidsson, CG Östenson… - Acta neuropathologica …, 2018 - Springer
Recent data suggest that olfactory deficits could represent an early marker and a pathogenic
mechanism at the basis of cognitive decline in type 2 diabetes (T2D). However, research is …

[HTML][HTML] Impaired olfactory system in metabolic imbalance-related neuropathology

DH Lee, J Song - Life Sciences, 2024 - Elsevier
Olfactory dysfunction, influenced by factors such as aging and environmental stress, is
linked to various neurological disorders. The olfactory bulb's connections to brain areas like …

The role of insulin sensitivity and intranasally applied insulin on olfactory perception

S Edwin Thanarajah, V Hoffstall, L Rigoux… - Scientific reports, 2019 - nature.com
Olfactory perception determines food selection behavior depending on energy homeostasis
and nutritional status. The mechanisms, however, by which metabolic signals in turn …

Associations of olfactory dysfunction with anthropometric and cardiometabolic measures: Findings from the 2013–2014 national health and nutrition examination …

S Gallo, L Byham-Gray, VB Duffy, HJ Hoffman… - Physiology & …, 2020 - Elsevier
We examined associations of olfactory dysfunction with anthropometric and cardiometabolic
measures in a nationally representative sample of US adults. In the 2013–2014 National …

Obesity-induced changes in lipid mediators persist after weight loss

A Hernandez-Carretero, N Weber… - International journal of …, 2018 - nature.com
Background: Obesity induces significant changes in lipid mediators, however, the extent to
which these changes persist after weight loss has not been investigated. Subjects/Methods …

Lipids and obesity: Also a matter of taste?

P Besnard - Reviews in Endocrine and Metabolic Disorders, 2016 - Springer
Obesity is undoubtedly one of the major public health challenges worldwide because of its
rapid progression and deleterious effects of associated diseases. The easier access to tasty …

Consumption of dietary fat causes loss of olfactory sensory neurons and associated circuitry that is not mitigated by voluntary exercise in mice

BM Chelette, AM Loeven, DN Gatlin… - The Journal of …, 2022 - Wiley Online Library
Excess nutrition causes loss of olfactory sensory neurons (OSNs) and reduces odour
discrimination and odour perception in mice. To separate diet‐induced obesity from the …