Recent advances in the label-free characterization of exosomes for cancer liquid biopsy: from scattering and spectroscopy to nanoindentation and nanodevices

R Di Santo, S Romanò, A Mazzini, S Jovanović… - Nanomaterials, 2021 - mdpi.com
Exosomes (EXOs) are nano-sized vesicles secreted by most cell types. They are abundant
in bio-fluids and harbor specific molecular constituents from their parental cells. Due to these …

Unlocking the diagnostic potential of saliva: A comprehensive review of infrared spectroscopy and its applications in salivary analysis

C Delrue, S De Bruyne, MM Speeckaert - Journal of Personalized …, 2023 - mdpi.com
Infrared (IR) spectroscopy is a noninvasive and rapid analytical technique that provides
information on the chemical composition, structure, and conformation of biomolecules in …

ATR-FTIR spectrum analysis of saliva samples from COVID-19 positive patients

A Martinez-Cuazitl, GJ Vazquez-Zapien… - Scientific Reports, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) is the latest biological hazard for the
novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though …

Salivary molecular spectroscopy: A sustainable, rapid and non-invasive monitoring tool for diabetes mellitus during insulin treatment

DC Caixeta, EMG Aguiar, L Cardoso-Sousa… - PLoS …, 2020 - journals.plos.org
Monitoring of blood glucose is an invasive, painful and costly practice in diabetes.
Consequently, the search for a more cost-effective (reagent-free), non-invasive and specific …

Soft and robust identification of body fluid using Fourier transform infrared spectroscopy and chemometric strategies for forensic analysis

A Takamura, K Watanabe, T Akutsu, T Ozawa - Scientific reports, 2018 - nature.com
Body fluid (BF) identification is a critical part of a criminal investigation because of its ability
to suggest how the crime was committed and to provide reliable origins of DNA. In contrast …

Saliva as a first-line diagnostic tool: A spectral challenge for identification of cancer biomarkers

C Paluszkiewicz, E Pięta, M Woźniak, N Piergies… - Journal of Molecular …, 2020 - Elsevier
The paper concentrates on the role of saliva in the early diagnosis of salivary gland tumor.
Due to the still not fully understood etiology of head and neck cancer, the fundamental …

Fourier Transform Infrared Spectroscopy as a useful tool for the automated classification of cancer cell-derived exosomes obtained under different culture conditions

S Romanò, F Di Giacinto, A Primiano, A Mazzini… - Analytica chimica …, 2020 - Elsevier
Exosomes possess great potential as cancer biomarkers in personalized medicine due to
their easy accessibility and capability of representing their parental cells. To boost the …

Pathology-specific molecular profiles of saliva in patients with multiple dental caries—potential application for predictive, preventive and personalised medical …

P Seredin, D Goloshchapov, Y Ippolitov, P Vongsvivut - Epma Journal, 2018 - Springer
Background Improving the quality of life is part of the global agenda. The focus is
predominantly on prevention of socially significant diseases. Combating dental caries …

Nanoparticles and human saliva: a step towards drug delivery systems for dental and craniofacial biomaterials

R Pokrowiecki, J Wojnarowicz, T Zareba… - International journal …, 2019 - Taylor & Francis
Aim The aims of this study were to investigate new nano-formulations based on ZnO and Ag
nanoparticle (NP) compounds when used against clinical strains of oral gram-positive and …

Ag-Contained Superabsorbent Curdlan–Chitosan Foams for Healing Wounds in a Type-2 Diabetic Mice Model

ES Permyakova, AS Konopatsky, KI Ershov… - Pharmaceutics, 2022 - mdpi.com
This study focused on the synthesis and characterization of pure curdlan–chitosan foams
(CUR/CS), as well as foams containing Ag nanoparticles (CUR/CS/Ag), and their effect on …