With increasing demand for donor organs for transplantation, machine perfusion (MP)
promises to be a beneficial alternative preservation method for donor livers, particularly …

The primary objective of organ preservation is to deliver a viable graft with minimal risk of
impaired postoperative graft function. In current clinical practice, preservation of transplanted …

Orthotopic liver transplantation is the only available treatment for severe liver failure, but it is
currently limited by organ shortage. One technical challenge that has thus far limited the …

The limited preservation duration of organs has contributed to the shortage of organs for
transplantation. Recently, a tripling of the storage duration was achieved with supercooling …

Current machine perfusion technology permits livers to be preserved ex situ for short periods
to assess viability prior to transplant. Long-term normothermic perfusion of livers is an …

The realization of long-term human organ preservation will have groundbreaking effects on
the current practice of transplantation. Herein we present a new technique based on …

Background & Aims The use of livers from donors after cardiac arrest (DCD) is increasing in
many countries to overcome organ shortage. Due to additional warm ischemia before …

Background & Aims A variety of liver perfusion techniques have been proposed to protect
liver grafts prior to implantation. We compared hypothermic and normothermic oxygenated …

The effects of normothermic machine perfusion (NMP) on the postreperfusion
hemodynamics and extrahepatic biliary duct histology of donation after cardiac death (DCD) …

BACKGROUND: The shortage in donor livers has led to increased use of allografts derived
from donation after cardiac death (DCD). The compromised viability in these livers leads to …