The mucosal tissues of the gastrointestinal, respiratory, reproductive, and urinary tracts, and
the surface of the eye present an enormous surface area to the exterior environment. All of …

The airway epithelium represents the first point of contact for inhaled foreign organisms. The
protective arsenal of the airway epithelium is provided in the form of physical barriers and a …

The intestinal tract is a complex ecosystem that combines resident microbiota and the cells
of various phenotypes with complex metabolic activities that line the epithelial wall. The …

Salmonella enterica serovar Typhimurium is a model organism used to explore the virulence
strategies underlying Salmonella pathogenesis. Although intestinal mucus is the first line of …

Transmembrane mucins are glycoproteins involved in barrier function in epithelial tissues.
To identify novel transmembrane mucin genes, we performed a tblastn search of the …

Cell surface mucin (cs-mucin) glycoproteins are constitutively expressed at the surface of
respiratory epithelia where pathogens such as influenza A virus (IAV) gain entry into cells …

Membrane-tethered mucins are large glycoproteins present in the glycocalyx along the
apical surface of all wet-surfaced epithelia of the body, including that of the ocular surface …

Pseudomonas aeruginosa is an opportunistic bacterial pathogen responsible for a high
incidence of acute and chronic pulmonary infection. These infections are particularly …

Airway mucus constitutes a thin layer of airway surface liquid with component
macromolecules that covers the luminal surface of the respiratory tract. The major function of …

Pseudomonas aeruginosa is an increasingly prevalent opportunistic pathogen that causes a
variety of nosocomial infections, life-threatening diseases in immunocompromised persons …