Stress-related neuropsychiatric disorders, such as major depressive disorder and posttraumatic stress disorder, exact enormous socioeconomic and individual consequences …
Social behaviors are among the most important motivated behaviors. How dopamine (DA), a" reward" signal, releases during social behaviors has been a topic of interest for decades …
Highlights•Chronic drug use alters the epigenetic state of neurons and other cell types within brain reward regions.•Epigenetic adaptations are correlated with addiction, but their causal …
Inappropriate and pathological aggression plays a leading role in the suffering and death of millions of people, and further places an untenable strain on the caregivers and families of …
Repeated cocaine use induces coordinated changes in gene expression that drive plasticity in the nucleus accumbens (NAc), an important component of the brain's reward circuitry, and …
Prosocial behavior, in particular helping others in need, occurs preferentially in response to distress of one's own group members. In order to explore the neural mechanisms promoting …
Aggression is an evolutionarily conserved, adaptive component of social behavior. Studies in male mice illustrate that aggression is influenced by numerous factors including the …
ME Flanigan, TL Kash - European Journal of Neuroscience, 2022 - Wiley Online Library
The bed nucleus of the stria terminalis (BNST) is a sexually dimorphic, neuropeptide‐rich node of the extended amygdala that has been implicated in responses to stress, drugs of …
LA Ramsey, FM Holloman, SS Lee, M Venniro - Nature Protocols, 2023 - nature.com
Little is known about how social factors contribute to neurobiology or neuropsychiatric disorders. The use of mice allows one to probe the neurobiological bases of social …