Cancer-derived extracellular vesicles (EVs) are regarded as having promising potential to
be used as therapeutics and disease biomarkers. Mechanistically, EVs have been shown to …

Efforts to develop anti-cancer therapies have largely focused on targeting the epithelial
compartment, despite the presence of non-neoplastic stromal components that substantially …

Metabolic reprogramming is reported to be one of the hallmarks of cancer, which is an
adaptive mechanism by which fast-growing cancer cells adapt to their increasing energy …

Cancer cells are well-known for adapting their metabolism to maintain high proliferation
rates and survive in unfavorable environments with low oxygen and nutritional deficiency …

Plants use extracellular vesicles (EVs) to transport small RNAs (sRNAs) into their fungal
pathogens and silence fungal virulence-related genes through a phenomenon called 'cross …

The tumor microenvironment is proposed to contribute substantially to the progression of
cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most …

Tumor metastasis is a hallmark of cancer. The communication between cancer-derived
exosomes and stroma plays an irreplaceable role in facilitating pre-metastatic niche …

Rationale: Breast cancer preferentially develops osteolytic bone metastasis, which makes
patients suffer from pain, fractures and spinal cord compression. Accumulating evidences …

Background & Aims Intrahepatic cholangiocarcinoma (ICC) is the second most common liver
malignancy. ICC typically features remarkable cellular heterogeneity and a dense stromal …

Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …