Biofilms are surface-attached groups of microbial cells encased in an extracellular matrix
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …

Daptomycin is a cyclic lipopeptide antibiotic used for the treatment of Gram-positive
infections including complicated skin and skin structure infections, right-sided infective …

Highlights•Superbugs such as MRSA are highly prevalent infections with high mortality
rates.•Biofilms and antibiotic resistance impede effective treatment of MRSA.•Conventional …

Background Infective endocarditis (IE) is associated with high rates of mortality. Prolonged
treatments with high-dose intravenous antibiotics often fail to eradicate the infection …

Antimicrobial-resistant (AMR) foodborne bacteria causing bacterial infections pose a serious
threat to human health. In addition, the ability of some of these bacteria to form biofilms …

Despite the discovery of antibiotics, the battle against bacteria is so far in their favor,
specifically because bugs are able to develop a superstructure named biofilm, to resist and …

Biofilms formed by methicillin-resistant S. aureus (MRSA) are among the most frequent
causes of biomedical device-related infection, which are difficult to treat and are often …

Antibiotic treatment failure of Staphylococcus aureus infections is very common. In addition
to genetically encoded mechanisms of antibiotic resistance, numerous additional factors …

The ability of Staphylococcus aureus to form biofilms and persisters is a major cause of
recalcitrant infections that are difficult to treat. We have examined time-dependent variation …

The influence of the biofilm matrix on molecular diffusion is commonly hypothesized to be
responsible for emergent characteristics of biofilms such as nutrient trapping, signal …