Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
Applications of surface modification technologies in nanomedicine for deep tumor penetration
Z Li, X Shan, Z Chen, N Gao, W Zeng… - Advanced …, 2021 - Wiley Online Library
The impermeable barrier of solid tumors due to the complexity of their components limits the
treatment effect of nanomedicine and hinders its clinical translation. Several methods are …
treatment effect of nanomedicine and hinders its clinical translation. Several methods are …
Pharmacology of heparin and related drugs: an update
J Hogwood, B Mulloy, R Lever, E Gray, CP Page… - Pharmacological …, 2023 - Elsevier
Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …
[HTML][HTML] A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative …
Polyetheretherketone (PEEK) is a desirable alternative to conventional biomedical metals
for orthopedic implants due to the excellent mechanical properties. However, the inherent …
for orthopedic implants due to the excellent mechanical properties. However, the inherent …
Advanced strategies to thwart foreign body response to implantable devices
Mitigating the foreign body response (FBR) to implantable medical devices (IMDs) is critical
for successful long‐term clinical deployment. The FBR is an inevitable immunological …
for successful long‐term clinical deployment. The FBR is an inevitable immunological …
Tuning the surface immunomodulatory functions of polyetheretherketone for enhanced osseointegration
The adverse macrophage-mediated immune response elicited by the surface of
polyetheretherketone (PEEK) is responsible for the formation of fibrous encapsulation and …
polyetheretherketone (PEEK) is responsible for the formation of fibrous encapsulation and …
Artificial small-diameter blood vessels: Materials, fabrication, surface modification, mechanical properties, and bioactive functionalities
D Wang, Y Xu, Q Li, LS Turng - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Cardiovascular diseases, especially ones involving narrowed or blocked blood vessels with
diameters smaller than 6 millimeters, are the leading cause of death globally. Vascular grafts …
diameters smaller than 6 millimeters, are the leading cause of death globally. Vascular grafts …
Epigallocatechin gallate mediated sandwich-like coating for mimicking endothelium with sustained therapeutic nitric oxide generation and heparin release
In-stent restenosis after stenting is generally characterized by an inflammatory response,
excessive proliferation of smooth muscle cells, and delayed healing of the endothelium …
excessive proliferation of smooth muscle cells, and delayed healing of the endothelium …
Transient blood thinning during extracorporeal blood purification via the inactivation of coagulation factors by hydrogel microspheres
During extracorporeal blood purification, anticoagulants are administered to prevent
thrombogenesis. However, haemorrhagic complications owing to near-complete inactivation …
thrombogenesis. However, haemorrhagic complications owing to near-complete inactivation …
Biomimetic engineering endothelium-like coating on cardiovascular stent through heparin and nitric oxide-generating compound synergistic modification strategy
Co-immobilization of two or more molecules with different and complementary functions to
prevent thrombosis, suppress smooth muscle cell (SMC) proliferation, and support …
prevent thrombosis, suppress smooth muscle cell (SMC) proliferation, and support …