Minimal genome: Worthwhile or worthless efforts toward being smaller?
Microbial cells are versatile hosts for the production of value‐added products due to the well‐
established background knowledge, various genetic tools, and ease of manipulation …
established background knowledge, various genetic tools, and ease of manipulation …
Construction of a minimal genome as a chassis for synthetic biology
Microbial diversity and complexity pose challenges in understanding the voluminous genetic
information produced from whole-genome sequences, bioinformatics and high-throughput ' …
information produced from whole-genome sequences, bioinformatics and high-throughput ' …
MinGenome: An In Silico Top-Down Approach for the Synthesis of Minimized Genomes
L Wang, CD Maranas - ACS synthetic biology, 2018 - ACS Publications
Genome minimized strains offer advantages as production chassis by reducing
transcriptional cost, eliminating competing functions and limiting unwanted regulatory …
transcriptional cost, eliminating competing functions and limiting unwanted regulatory …
Evolution and function of the Mycoplasma hyopneumoniae peroxiredoxin, a 2-Cys-like enzyme with a single Cys residue
T Gonchoroski, VG Virginio, CE Thompson… - Molecular genetics and …, 2017 - Springer
The minimal genome of the mollicute Mycoplasma hyopneumoniae, the etiological agent of
porcine enzootic pneumonia, encodes a limited repertoire of antioxidant enzymes that …
porcine enzootic pneumonia, encodes a limited repertoire of antioxidant enzymes that …
Reconstructing gene content in the last common ancestor of cellular life: is it possible, should it be done, and are we making any progress?
A Mushegian - bioRxiv, 2014 - biorxiv.org
I review recent literature on the reconstruction of gene repertoire of the Last Universal
Common Ancestor of cellular life (LUCA). The form of the phylogenetic record of cellular life …
Common Ancestor of cellular life (LUCA). The form of the phylogenetic record of cellular life …
[PDF][PDF] Mechanistic Insights into the Auto-Regulation of PTEN and Its Related HECT E3 Ligases
Z Chen - 2017 - jscholarship.library.jhu.edu
PTEN (phosphatase and tensin homolog deleted on chromosome 10) is a lipid phosphatase
that dephosphorylates PIP3 to PIP2, and negatively regulates the PI3K/AKT signaling …
that dephosphorylates PIP3 to PIP2, and negatively regulates the PI3K/AKT signaling …