Cell surface carbohydrates have been proven optimal targets for vaccine development.
Conjugation of polysaccharides to a carrier protein triggers a T-cell-dependent immune …

The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Vibrio cholerae is a prototypical noninvasive mucosal pathogen, yet infection generates long-
lasting protection against subsequent disease. Vibriocidal antibody responses are an …

We characterized the acute B cell response in adults with cholera by analyzing the
repertoire, specificity, and functional characteristics of 138 monoclonal antibodies (MAbs) …

Cholera is a severe diarrheal disease caused by the bacterium Vibrio cholerae and
constitutes a significant public health threat in many areas of the world. V. cholerae infection …

Vibrio cholerae is the causative agent of cholera, a highly contagious diarrheal disease
affecting millions worldwide each year. Cholera is a major public health problem, primarily in …

Introduction The public health burden caused by pathogenic Gram-negative bacteria is
increasingly prominent due to antimicrobial resistance. The surface carbohydrates are …

Vibrio cholerae, a noninvasive mucosal pathogen, is endemic in more than 50 countries.
Oral cholera vaccines, based on killed whole-cell strains of Vibrio cholerae, can provide …

There is a need for vaccines effective against shigella infection in young children in resource-
limited areas. Protective immunity against shigella infection targets the O-specific …

The vaccine elicitation of broadly neutralizing antibodies against HIV-1 is a long-sought
goal. We previously reported the amino-terminal eight residues of the HIV-1-fusion peptide …