Preeclampsia (PE) affects 5–7% of all pregnancies in the United States and is the leading
cause of maternal and prenatal morbidity. PE is associated with hypertension after week 20 …

Preterm birth is the leading cause of neonatal morbidity and mortality. Although the
underlying causes of pregnancy-associated complication are numerous, it is well …

Introduction The pro‐and anti‐inflammatory cytokines play crucial role in the development
and functions of placenta. Any changes in these cytokines may be associated with many …

Inflammation mediated by both innate and adaptive immune cells is necessary for several
important processes during pregnancy. Pro-inflammatory immune cell activation plays a …

At the time of implantation, the trophoblast cells of the embryo adhere and then invade into
the maternal endometrium and eventually establish placentation. The endometrium at the …

The implicit paradigm that has governed the study and clinical management of preterm
labour is that term and preterm parturition are the same processes, except for the gestational …

A successful pregnancy requires that the maternal immune system is instructed to a state of
tolerance to avoid rejection of the semiallogeneic fetal–placental unit. Although increasing …

Inflammation has been implicated in the mechanisms responsible for preterm and term
parturition, as well as fetal injury. Out of all of the suspected causes of preterm labor and …

Inflammation has been implicated in the mechanisms responsible for preterm and term
parturition, as well as fetal injury. Out of all of the suspected causes of preterm labour and …

The central role of the placenta in the pathogenesis of pre-eclampsia is undisputed. The
evidence that maternal syndrome of pre-eclampsia is caused by a maternal systemic …