Cancer, which is the uncontrolled growth of cells, is the second leading cause of death after
heart disease. Targeting drugs, especially to specific genes and proteins involved in growth …

Morpholine is a heterocycle featured in numerous approved and experimental drugs as well
as bioactive molecules. It is often employed in the field of medicinal chemistry for its …

Morpholine is a versatile moiety, a privileged pharmacophore and an outstanding
heterocyclic motif with wide ranges of pharmacological activities due to different …

Benzimidazole, the benzo derivative of imidazole, is a class of bicyclic aromatic organic
compound consisting of six‐membered benzene ring fused to five‐membered imidazole at 4 …

Developing drugs for the central nervous system (CNS) requires fine chemical modifications,
as a strict balance between size and lipophilicity is necessary to improve the permeability …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading
cause of dementia worldwide. The limited pharmacological approaches based on …

An electrochemical intramolecular oxytrifluoromethylation of N-tethered alkenyl alcohols
was developed providing straightforward access to CF3-containing morpholines derivatives …

A series of novel indole based sulfonohydrazide derivatives (5a–k) containing morpholine
heterocyclic ring were synthesized through multistep chemical reactions. The target …

The CuI promoted one‐pot multi‐component synthesis of new fused [1, 2, 3] triazolo [5, 1‐a]
isoquinoline derivatives (4 a–4 h, 8 a–8 f & 9 a–9 f) without isolating unsafe azides and their …

To expand the array of chemotherapeutic drugs, earth-abundant metal complexes are found
to be the future direction. In this regard, new zinc (II) complexes 1–3 of 8-aminoquinoline …