While the crucial role of intrinsically disordered proteins (IDPs) in the cell cycle is now
recognized, deciphering their molecular mode of action at the structural level still remains …

Posttranscriptional regulation of RNA metabolism, including RNA processing, intron splicing,
editing, RNA export, and decay, is increasingly regarded as an essential step for fine-tuning …

Abstract The Ribosome Binding Site (RBS) Calculator is a design method for predicting and
controlling translation initiation and protein expression in bacteria. The method can predict …

To survive under conditions of stress, such as nutrient deprivation, bacterial 70S ribosomes
dimerize to form hibernating 100S particles. In γ-proteobacteria, such as Escherichia coli …

Regulation of translation initiation is well appropriate to adapt cell growth in response to
stress and environmental changes. Many bacterial mRNAs adopt structures in their 5 …

Heat stress commonly leads to inhibition of photosynthesis in higher plants. The
transcriptional induction of heat stress-responsive genes represents the first line of inducible …

The sequence and secondary structure of the 5′-end of mRNAs regulate translation by
controlling ribosome initiation on the mRNA. Ribosomal protein S1 is crucial for ribosome …

Escherichia coli ribosomal protein S1 is required for the translation initiation of messenger
RNAs, in particular when their Shine–Dalgarno sequence is degenerated. Closely related …

In all organisms, RNA-binding proteins participate in modulating all the steps in the life cycle
of RNA, including transcription, folding, translation and turnover. In bacteria, RNA-binding …

Pyrazinamide (PZA) is a first‐line drug for tuberculosis (TB) treatment and is responsible for
shortening the duration of TB therapy. The mode of action of PZA remains elusive. RpsA, the …