Adaptive immunity: an emerging player in the progression of NAFLD

S Sutti, E Albano - Nature Reviews Gastroenterology & Hepatology, 2020 - nature.com
In the past decade, nonalcoholic fatty liver disease (NAFLD) has become a leading cause of
chronic liver disease and cirrhosis, as well as an important risk factor for hepatocellular …

Lipid peroxidation-derived aldehydes, 4-hydroxynonenal and malondialdehyde in aging-related disorders

G Barrera, S Pizzimenti, M Daga, C Dianzani, A Arcaro… - Antioxidants, 2018 - mdpi.com
Among the various mechanisms involved in aging, it was proposed long ago that a
prominent role is played by oxidative stress. A major way by which the latter can provoke …

Regulated necrosis in atherosclerosis

P Puylaert, M Zurek, KJ Rayner… - … , and vascular biology, 2022 - Am Heart Assoc
During atherosclerosis, lipid-rich plaques are formed in large-and medium-sized arteries,
which can reduce blood flow to tissues. This situation becomes particularly precarious when …

Lipid peroxidation in atherosclerotic cardiovascular diseases

E Gianazza, M Brioschi… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …

Role of DAMPs in respiratory virus-induced acute respiratory distress syndrome—with a preliminary reference to SARS-CoV-2 pneumonia

WG Land - Genes & Immunity, 2021 - nature.com
When surveying the current literature on COVID-19, the “cytokine storm” is considered to be
pathogenetically involved in its severe outcomes such as acute respiratory distress …

The why and how of adaptive immune responses in ischemic cardiovascular disease

Z Mallat, CJ Binder - Nature cardiovascular research, 2022 - nature.com
Atherosclerotic cardiovascular disease is a major cause of disability and death worldwide.
Most therapeutic approaches target traditional risk factors but ignore the fundamental role of …

[PDF][PDF] Early detection and curative treatment of hepatocellular carcinoma: a cost‐effectiveness analysis in France and in the United States

B Cadier, J Bulsei, P Nahon, O Seror, A Laurent… - …, 2017 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the leading cause of death in patients with cirrhosis.
Patients outside clinical trials seldom benefit from evidence‐based monitoring. The objective …

Malondialdehyde epitopes as mediators of sterile inflammation

CJ Busch, CJ Binder - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2017 - Elsevier
Enhanced lipid peroxidation occurs during oxidative stress and results in the generation of
lipid peroxidation end products such as malondialdehyde (MDA), which can attach to …

Immunity as cornerstone of non-alcoholic fatty liver disease: the contribution of oxidative stress in the disease progression

M Dallio, M Sangineto, M Romeo, R Villani… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of
metabolic syndrome and has become the major cause of chronic liver disease, especially in …

Effect of particulate matter-bound metals exposure on prothrombotic biomarkers: a systematic review

S Santo Signorelli, GO Conti, A Zanobetti… - Environmental …, 2019 - Elsevier
Environmental pollution is an important modifiable determinant for preventing
cardiovascular diseases. Acute exposure to air pollution is linked to severe adverse …