Cancer is currently ineffectively treated using therapeutic drugs, and is also able to resist
drug action, resulting in increased side effects following drug treatment. A novel therapeutic …

Extensive research has been undertaken in the pursuit of anticancer therapeutics. Many
anticancer drugs require specificity of delivery to cancer cells, whilst sparing healthy tissue …

Lipopeptides are amphiphilic peptides in which an aliphatic chain is attached to either the C
or N terminus of peptides. Their self-assembly—into micelles, vesicles, nanotubes, fibres or …

Peptides are naturally produced by all organisms and exhibit a wide range of physiological,
immunomodulatory, and wound healing functions. Furthermore, they can provide with …

Despite the rapid development of novel drug delivery systems, the limited intratumor
accumulation of drugs and immunomodulatory function of drug nanovehicles still limit their …

Despite the increasing number of effective therapeutics for eye diseases, their treatment is
still challenging due to the presence of effective barriers protecting eye tissues. Cell …

The ingrained mechanical robustness of amyloids in association with their fine-tunable
physicochemical properties results in the rational design and synthesis of tailor-made …

SwissDrugDesign is an important initiative led by the Molecular Modeling Group of the SIB
Swiss Institute of Bioinformatics. This project provides a collection of freely available online …

Introduction Cell-penetrating peptide (CPP) technologies represent an important strategy to
address drug delivery to specific intracellular compartments by covalent conjugation to …

Cancer treatments that combine chemotherapy with immunotherapy are becoming
increasingly effective, but chemotherapy is generally considered to have …