Mercury is a toxic and hazardous metal that occurs naturally in the earth's crust. Natural
phenomena such as erosion and volcanic eruptions, and anthropogenic activities like metal …

▪ Abstract Apoptosis of mature T lymphocytes preserves peripheral homeostasis and
tolerance by countering the profound changes in the number and types of T cells stimulated …

Lymphadenopathy in children for which no infectious or malignant cause can be ascertained
constitutes a challenging diagnostic dilemma. Autoimmune lymphoproliferative syndrome …

Lymphomas were studied in kindreds with autoimmune lymphoproliferative syndrome
(ALPS; Canale-Smith syndrome), a disorder of lymphocyte homeostasis usually associated …

Caspases are cysteine proteases that mediate programmed cell death in phylogenetically
diverse multicellular organisms. We report here two kindreds with autoimmune …

The autoimmune lymphoproliferative syndrome (ALPS) affords novel insights into the
mechanisms that regulate lymphocyte homeostasis and underlie the development of …

Programmed cell death, or apoptosis, is well documented as a physiological means of
eliminating activated lymphocytes and maintaining immune homeostasis. Apoptosis has …

The defects in lymphocyte apoptosis that underlie the autoimmune lymphoproliferative
syndrome (ALPS) are usually attributable to inherited mutations of the CD95 (Fas) gene. In …

Autoimmune lymphoproliferative syndrome (ALPS) is a rare disorder of disrupted
lymphocyte homeostasis. Clinical manifestations of ALPS vary but typically include …

Autoimmune lymphoproliferative syndrome (ALPS) is a primary immune regulatory disorder
characterized by benign or malignant lymphoproliferation and autoimmunity. Classically …