On the expansion of biological functions of lytic polysaccharide monooxygenases

TM Vandhana, JL Reyre, D Sushmaa… - New …, 2022 - Wiley Online Library
Lytic polysaccharide monooxygenases (LPMOs) constitute an enigmatic class of enzymes,
the discovery of which has opened up a new arena of riveting research. LPMOs can …

The hidden power of secondary metabolites in plant-fungi interactions and sustainable phytoremediation

NA Elhamouly, OA Hewedy, A Zaitoon… - Frontiers in Plant …, 2022 - frontiersin.org
The global environment is dominated by various small exotic substances, known as
secondary metabolites, produced by plants and microorganisms. Plants and fungi are …

Lytic polysaccharide monooxygenases: enzymes for controlled and site-specific Fenton-like chemistry

B Bissaro, VGH Eijsink - Essays in biochemistry, 2023 - portlandpress.com
The discovery of oxidative cleavage of glycosidic bonds by enzymes currently known as lytic
polysaccharide monooxygenases (LPMOs) has profoundly changed our current …

Emergence of the fungal immune system

A Daskalov - Iscience, 2023 - cell.com
Investigation of fungal biology has been frequently motivated by the fact that many fungal
species are important plant and animal pathogens. Such efforts have contributed …

Scission of Glucosidic Bonds by a Lentinus similis Lytic Polysaccharide Monooxygenases Is Strictly Dependent on H2O2 while the Oxidation of Saccharide Products Depends …

S Brander, R Tokin, JØ Ipsen, PE Jensen… - ACS …, 2021 - ACS Publications
Lytic polysaccharide monooxygenases (LPMOs) are mononuclear copper enzymes that act
in synergy with glycoside hydrolases to saccharify the most abundant polysaccharides in …

A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen Cryptococcus …

C Probst, M Hallas-Møller, JØ Ipsen, JT Brooks… - PLOS …, 2023 - journals.plos.org
Fungi often adapt to environmental stress by altering their size, shape, or rate of cell division.
These morphological changes require reorganization of the cell wall, a structural feature …

A dialogue-like cell communication mechanism is conserved in filamentous ascomycete fungi and mediates interspecies interactions

H Haj Hammadeh, A Serrano… - Proceedings of the …, 2022 - National Acad Sciences
In many filamentous fungi, germinating spores cooperate by fusing into supracellular
structures, which develop into the mycelial colony. In the model fungus Neurospora crassa …

A moonlighting function of a chitin polysaccharide monooxygenase, CWR-1, in Neurospora crassa allorecognition

TC Detomasi, AM Rico-Ramírez, RI Sayler… - elife, 2022 - elifesciences.org
Organisms require the ability to differentiate themselves from organisms of different or even
the same species. Allorecognition processes in filamentous fungi are essential to ensure …

Syncytia in fungi

AP Mela, AM Rico-Ramírez, NL Glass - Cells, 2020 - mdpi.com
Filamentous fungi typically grow as interconnected multinucleate syncytia that can be
microscopic to many hectares in size. Mechanistic details and rules that govern the …

[HTML][HTML] Fungi took a unique evolutionary route to multicellularity: Seven key challenges for fungal multicellular life

LG Nagy, T Varga, Á Csernetics, M Virágh - Fungal Biology Reviews, 2020 - Elsevier
The evolution of multicellularity has been one of the major transitions in the history of life. In
contrast to animals and plants, how multicellularity evolved in fungi and how it compares to …