Lipid metabolic reprogramming in cancer cells

S Beloribi-Djefaflia, S Vasseur, F Guillaumond - Oncogenesis, 2016 - nature.com
Many human diseases, including metabolic, immune and central nervous system disorders,
as well as cancer, are the consequence of an alteration in lipid metabolic enzymes and their …

Applications of Raman spectroscopy in cancer diagnosis

GW Auner, SK Koya, C Huang, B Broadbent… - Cancer and Metastasis …, 2018 - Springer
Novel approaches toward understanding the evolution of disease can lead to the discovery
of biomarkers that will enable better management of disease progression and improve …

Bright near-infrared aggregation-induced emission luminogens with strong two-photon absorption, excellent organelle specificity, and efficient photodynamic therapy …

Z Zheng, T Zhang, H Liu, Y Chen, RTK Kwok, C Ma… - Acs Nano, 2018 - ACS Publications
Far-red and near-infrared (NIR) fluorescent materials possessing the characteristics of
strong two-photon absorption and aggregation-induced emission (AIE) as well as specific …

Super-resolution SRS microscopy with A-PoD

H Jang, Y Li, AA Fung, P Bagheri, K Hoang… - Nature …, 2023 - nature.com
Stimulated Raman scattering (SRS) offers the ability to image metabolic dynamics with high
signal-to-noise ratio. However, its spatial resolution is limited by the numerical aperture of …

Ultrabright and fluorogenic probes for multicolor imaging and tracking of lipid droplets in cells and tissues

M Collot, TK Fam, P Ashokkumar… - Journal of the …, 2018 - ACS Publications
Lipid droplets (LDs) are intracellular lipid-rich organelles that regulate the storage of neutral
lipids and were recently found to be involved in many physiological processes, metabolic …

Recent advances in fluorescent probes for lipid droplets

TK Fam, AS Klymchenko, M Collot - Materials, 2018 - mdpi.com
Lipid droplets (LDs) are organelles that serve as the storage of intracellular neutral lipids.
LDs regulate many physiological processes. They recently attracted attention after extensive …

Metabolic reprogramming in triple-negative breast cancer

X Sun, M Wang, M Wang, X Yu, J Guo, T Sun… - Frontiers in …, 2020 - frontiersin.org
Metabolic reprogramming is an emerging hallmark of cancer cells, in which cancer cells
exhibit distinct metabolic phenotypes to fuel their proliferation and progression. The …

Non-coding RNAs: the new central dogma of cancer biology

PE Saw, X Xu, J Chen, EW Song - Science China Life Sciences, 2021 - Springer
The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …

Emerging designs of aggregation-induced emission luminogens for lipid droplets imaging

F Zhang, X Wu, B Liu, T Han, D Yan, D Wang… - Coordination Chemistry …, 2023 - Elsevier
Lipid droplets (LDs) are organelles that have evolved to store intracellular neutral lipids and
maintain cellular energy homeostasis. Once considered as inert fat particles, they have …

A Bright Two‐Photon Lipid Droplets Probe with Viscosity‐Enhanced Solvatochromic Emission for Visualizing Lipid Metabolic Disorders in Deep Tissues

Z Zheng, Y Yang, P Wang, X Gou… - Advanced Functional …, 2023 - Wiley Online Library
The polarity of lipid droplets (LDs) plays an important role in pathological processes
associated with abnormal lipid metabolism. Monitoring the variation of LDs polarity in cells …