Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate

L Ginini, S Billan, E Fridman, Z Gil - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …

Emerging role of exosomes as biomarkers in cancer treatment and diagnosis

NA Hanjani, N Esmaelizad, S Zanganeh… - Critical reviews in …, 2022 - Elsevier
Cancer is a leading cause of death worldwide and cancer incidence and mortality are
rapidly growing. These massive amounts of cancer patients require rapid diagnosis and …

Investigating the regulatory role of miRNAs as silent conductors in the management of pathogenesis and therapeutic resistance of pancreatic cancer

AI Abulsoud, SS Elshaer, NM Abdelmaksoud… - … -Research and Practice, 2023 - Elsevier
Pancreatic cancer (PC) has the greatest mortality rate of all the main malignancies. Its
advanced stage and poor prognosis place it at the bottom of all cancer sites. Hence …

Targeting miRNA and using miRNA as potential therapeutic options to bypass resistance in pancreatic ductal adenocarcinoma

M Vahabi, B Dehni, I Antomás, E Giovannetti… - Cancer and Metastasis …, 2023 - Springer
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with poor
prognosis due to early metastasis, low diagnostic rates at early stages, and resistance to …

Role of non-coding RNAs in tumor progression and metastasis in pancreatic cancer

LF Sempere, K Powell, J Rana, AA Brock… - Cancer and Metastasis …, 2021 - Springer
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of cancer with an
overall 5-year survival rate of less than 10%. The 1-year survival rate of patients with locally …

Identification of exosomal hsa-miR-483-5p as a potential biomarker for hepatocellular carcinoma via microRNA expression profiling of tumor-derived exosomes

J Lin, W Lin, Y Bai, Y Liao, Q Lin, L Chen… - Experimental Cell …, 2022 - Elsevier
To date, most studies of exosomes related to hepatocellular carcinoma (HCC) have used
commercial cancer cell lines or patient plasma as source material. In this study, we isolated …

The emerging roles of exosomal long non‐coding RNAs in bladder cancer

Q Liu - Journal of cellular and molecular medicine, 2022 - Wiley Online Library
Extracellular vesicles (EVs), especially exosomes, have been reported to play essential
roles as extracellular messengers by transporting goods in various diseases, while their …

Pancreatic cancer and exosomes: role in progression, diagnosis, monitoring, and treatment

X Fang, H Lan, K Jin, J Qian - Frontiers in Oncology, 2023 - frontiersin.org
Pancreatic cancer (PC) is one of the most dangerous diseases that threaten human life, and
investigating the details affecting its progression or regression is particularly important …

[HTML][HTML] Circ_0006790 carried by bone marrow mesenchymal stem cell-derived exosomes regulates S100A11 DNA methylation through binding to CBX7 in …

G Gao, L Wang, C Li - American Journal of Cancer Research, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, particularly exosomes, play a vital role via their cargoes. Their
potential in pancreatic ductal adenocarcinoma (PDAC), one of the leading causes of cancer …

Micrornas associated with gemcitabine resistance via emt, tme, and drug metabolism in pancreatic cancer

N Funamizu, M Honjo, K Tamura, K Sakamoto… - Cancers, 2023 - mdpi.com
Simple Summary We herein reviewed the current evidence for the role of microRNAs
(miRNAs) in the mechanism of chemoresistance in pancreatic cancer. Pancreatic cancer …