Many complex traits or diseases, such as infectious and autoimmune diseases, cancer,
xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the …

Preeclampsia is one of the most common obstetrical complications worldwide. The
pathomechanism of this disease begins with abnormal placentation in early pregnancy …

The placenta is a vital organ of pregnancy, regulating adaptation to pregnancy, gestational
parent/fetal exchange, and ultimately, fetal development and growth. Not surprisingly, in …

An intricate interplay between genetic and environmental factors contributes to the
development of type 2 diabetes (T2D) and its complications. Therefore, it is not surprising …

Herein we trace links between biochemical pathways, pathogenesis, and metabolic
diseases to set the stage for new therapeutic advances. Cellular and acellular …

The benefits of regular physical activity are related to delaying and reversing the onset of
ageing and age-related disorders, including cardiomyopathy, neurodegenerative diseases …

Cardiovascular disease (CVD) is the biggest killer worldwide, composing a major economic
burden for health care systems. Obesity and diabetes are dual epidemics on the rise and …

Rhabdomyolysis-induced acute kidney injury (RIAKI) occurs following damage to the
muscular sarcolemma sheath, resulting in the leakage of myoglobin and other metabolites …

Maternal obesity (MO) and gestational diabetes mellitus (GDM) are common in Western
societies, which impair fetal development and predispose offspring to metabolic dysfunction …

Insufficient cytotrophoblast (CTB) migration and invasion into the maternal myometrium
leads to pregnancy related complications like Intra-uterus Growth Restriction (IUGR), and …