Patterns of linkage disequilibrium in the human genome

KG Ardlie, L Kruglyak, M Seielstad - Nature Reviews Genetics, 2002 - nature.com
Particular alleles at neighbouring loci tend to be co-inherited. For tightly linked loci, this
might lead to associations between alleles in the population—a property known as linkage …

Analysis of selection on enzyme polymorphisms

WF Eanes - Annual Review of Ecology and Systematics, 1999 - annualreviews.org
▪ Abstract Allozyme polymorphisms have been the focus of studies of selection at single
enzyme loci, and most involve the enzymes of central metabolism. DNA sequencing of …

A simple and robust statistical test for detecting the presence of recombination

TC Bruen, H Philippe, D Bryant - Genetics, 2006 - academic.oup.com
Recombination is a powerful evolutionary force that merges historically distinct genotypes.
But the extent of recombination within many organisms is unknown, and even determining …

[图书][B] Evolution through genetic exchange

ML Arnold - 2006 - books.google.com
Even before the publication of Darwin's Origin of Species, the perception of evolutionary
change has been a tree-like pattern of diversification-with divergent branches spreading …

Within-Host Evolution of Staphylococcus aureus during Asymptomatic Carriage

T Golubchik, EM Batty, RR Miller, H Farr, BC Young… - PloS one, 2013 - journals.plos.org
Background Staphylococcus aureus is a major cause of healthcare associated mortality, but
like many important bacterial pathogens, it is a common constituent of the normal human …

Whole genome linkage disequilibrium maps in cattle

SD McKay, RD Schnabel, BM Murdoch… - BMC genetics, 2007 - Springer
Background Bovine whole genome linkage disequilibrium maps were constructed for eight
breeds of cattle. These data provide fundamental information concerning bovine genome …

[图书][B] On the wings of checkerspots: a model system for population biology

PR Ehrlich, I Hanski - 2004 - books.google.com
Hanski, a leading thinker in metapopulation ecology, studies checkerspot butterfly
populations in Finland. Ehrlich, one of the leading ecologists and conservation biologist …

Linkage disequilibrium and recombination in hominid mitochondrial DNA

P Awadalla, A Eyre-Walker, JM Smith - Science, 1999 - science.org
The assumption that human mitochondrial DNA is inherited from one parent only and
therefore does not recombine is questionable. Linkage disequilibrium in human and …

High recombination rate in natural populations of Plasmodium falciparum

DJ Conway, C Roper, AMJ Oduola… - Proceedings of the …, 1999 - National Acad Sciences
Malaria parasites are sexually reproducing protozoa, although the extent of effective meiotic
recombination in natural populations has been debated. If meiotic recombination occurs …

[图书][B] Selection in natural populations

JB Mitton - 2000 - books.google.com
In 1974, Richard Lewontin published The Genetic Basis of Evolutionary Change, focusing
enormous attention on protein variation as both a model of underlying genetic variation and …